Prediction of a Stable Complex of Compounds in the Ethanol Extract of Celery Leaves (Apium graveolens L.) Function as a VKORC1 Antagonist.

A Asnawi, M Nedja, E Febrina… - Tropical Journal of …, 2023 - search.ebscohost.com
The vitamin K cycle, specifically the protein VKORC1 (Vitamin K epoxide reductase complex
subunit 1), is closely linked to coagulation mechanisms in the body. Disruptions in this cycle …

[PDF][PDF] Hepatoprotective study of Indonesian water kefir against CCl4-induced liver injury in rats

W Aligita, M Singgih, E Sutrisno… - J. Pharm. Pharmacogn …, 2023 - academia.edu
Context: Water kefir is a fermented beverage that is typically made in the home by
inoculating a sugar-rich solution with a microbial community (water kefir grains). Several …

[PDF][PDF] Identification of flavonoids from Acalypha indica L.(Euphorbiaceae) as caspase-3 activators using molecular docking and molecular dynamics

E Febrina, A Asnawi, R Abdulah, K Lestari… - Int J Appl …, 2022 - academia.edu
Objective: The purpose of this study was to determine the structural-based molecular
interactions between flavonoids contained in Acalypha indica L. and caspase-3 by …

[PDF][PDF] Molecular dynamics simulations of the caffeic acid interactions to dipeptidyl peptidase IV

EP Istyastono, FDO Riswanto - Int. J. Appl. Pharm, 2022 - academia.edu
Objective: The research presented in this article aimed to examine the applicability of a
recently published software PyPLIF HIPPOS to identify the interactions hotspots between …

[PDF][PDF] Screening of ashitaba (Angelica keiskei K.) compounds as potential Mycobacterium tuberculosis kasa inhibitors

A Asnawi, E Febrina, W Aligita, D Kurnia, LO Aman… - Int J Appl …, 2022 - academia.edu
Objective: Tuberculosis (TB) is a major global issue, mainly owing to the emergence of
antibiotic-resistant strains of the disease's causative agent, Mycobacterium tuberculosis. The …

The cytotoxic and apoptotic activity of Costus speciosus (Koenig) Smith (Costaceae) leaves against MCF-7 and HeLa cells

E Halimah, G Wilar, FF Sofian… - Journal of Herbmed …, 2024 - herbmedpharmacol.com
Abstract Introduction: Costus cuspidatus and Costus subsessilis have shown cytotoxic
effects in HL60, Jurkat, and THP-1 cells. This study aimed to evaluate the cytotoxicity and …

[PDF][PDF] Molecular docking and dynamics studies of 8, 9-dimethoxy ellagic acid contained in Peperomia pellucida (L.) Kunth against various diabetes mellitus receptors

Y Susilawati, RB Indradi, A Asnawi… - Journal of Pharmacy & …, 2024 - jppres.com
Context: The search for antidiabetic drugs that target the receptors involved in diabetes has
received significant attention in recent years. Peperomia pellucida (L.) Kunth's ethanol …

[HTML][HTML] Hepatoprotective properties of water kefir: A traditional fermented drink and its potential role

W Aligita, M Singgih, E Sutrisno… - International journal of …, 2023 - journals.lww.com
The liver is extremely vulnerable to damage because of its role in metabolism. Toxin,
metabolic syndrome, alcohol, microorganisms, and autoimmune diseases can be the cause …

[PDF][PDF] EXPLORING BINDING AFFINITIES OF ACETOACETATE IN ACRYLAMIDE-BASED POLYMERS (PAM) FOR MOLECULARLY IMPRINTED POLYMERS (MIPS) …

A ASNAWI, E FEBRINA, A LA ODE, F RAZI - 2023 - academia.edu
ABSTRACT Objective: Molecularly Imprinted Polymers (MIPs) have garnered significant
attention as promising materials for the selective recognition of target molecules …

[HTML][HTML] Molecular docking and dynamics studies of 8, 9-dimethoxy ellagic acid

Context: The search for antidiabetic drugs that target the receptors involved in diabetes has
received significant attention in recent years. Peperomia pellucida (L.) Kunth's ethanol …