The relationship between SARS-CoV-2 infection and type 1 diabetes mellitus

C Debuysschere, MP Nekoua, EK Alidjinou… - Nature Reviews …, 2024 - nature.com
Environmental factors, in particular viral infections, are thought to have an important role in
the pathogenesis of type 1 diabetes mellitus (T1DM). The COVID-19 pandemic reinforced …

Immunological and virological triggers of type 1 diabetes: insights and implications

JRN Lemos, K Hirani, M von Herrath - Frontiers in Immunology, 2024 - frontiersin.org
Type 1 diabetes (T1D) is caused by an autoimmune process which culminates in the
destruction of insulin-producing beta cells in the pancreas. It is widely believed that a …

Incidence of Type 1 Diabetes in Children Has Fallen to Pre–COVID-19 Pandemic Levels: A Population-Wide Analysis From Scotland

W Berthon, SJ McGurnaghan, LAK Blackbourn… - Diabetes …, 2024 - Am Diabetes Assoc
We previously reported in Diabetes Care (1) that the incidence of type 1 diabetes among
children aged 0–14 years in Scotland during 2020–2021 was 20% higher than the 7-year …

Clinical and immunological characteristics of children diagnosed with—Type 1 diabetes during the COVID‐19 pandemic

MG Margolis, S Weizman, L Lazar… - Diabetic …, 2024 - Wiley Online Library
Aims To find clinical and immunological signatures of the SARS‐CoV‐2 and the COVID‐19
pandemic on children newly diagnosed with type 1 diabetes (T1D). Methods A single …

Disruption to Pattern but No Overall Increase in the Expected Incidence of Pediatric Diabetes During the First Three Years of the COVID-19 Pandemic in Ontario …

R Shulman, E Cohen, TA Stukel, C Diong… - Diabetes …, 2024 - Am Diabetes Assoc
There is an emerging concern that the incidence of pediatric diabetes has increased since
the coronavirus disease 2019 (COVID-19) pandemic. We previously reported a slightly …

Spatiotemporal association between COVID-19 incidence and type 1 diabetes incidence among children and adolescents: a register-based ecological study in …

J Rosenbauer, A Stahl-Pehe, C Baechle… - Frontiers in …, 2024 - frontiersin.org
Objective Studies have shown an increased incidence of pediatric type 1 diabetes during
the COVID-19 pandemic, but the detailed role of SARS-CoV-2 infection in the incidence …

Infection episodes and islet autoantibodies in children at increased risk for type 1 diabetes before and during the COVID-19 pandemic

I Zeller, A Weiss, S Arnolds, K Schütte-Borkovec… - Infection, 2024 - Springer
Objectives To determine the impact of the COVID-19 pandemic on the incidence rates of
infection and islet autoimmunity in children at risk for type 1 diabetes. Methods 1050 children …

[HTML][HTML] Impact of the COVID-19 pandemic on temporal trends of biological indicators of autoimmunity

E Van Regemorter, G Zorzi, A Scohy, D Gruson… - Journal of Translational …, 2023 - Elsevier
Abstract Background and objective Coronavirus Disease 2019 (COVID-19) has been
associated with the onset of autoimmune conditions, but whether this relationship is causal …

Type 1 diabetes risk and severity after SARS-CoV-2 infection or vaccination

LC Stene, P Lopez-Doriga Ruiz, R Ljung, H Boas… - medRxiv, 2024 - medrxiv.org
Aim: To clarify whether SARS-CoV-2 infection or vaccination contribute to risk of type 1
diabetes or more severe diabetes onset in children and young adults. Methods: We …

Prevalence and Incidence of Medication-Treated Diabetes and Pattern of Glucose-Lowering Treatment During the COVID-19 Pandemic: Real-World Data from the …

C Siafarikas, G Karamanakos… - Experimental and …, 2024 - thieme-connect.com
Objectives This study aimed to investigate the prevalence and incidence of medication-
treated diabetes mellitus and the evolving patterns of glucose-lowering treatments the year …