Contrasting the equal contribution of nuclear genetic material from maternal and paternal
sources to offspring, passage of mitochondria, and thus mitochondrial DNA (mtDNA), is …

Mitochondrial supplementation was proposed as a complementary treatment to assisted
reproductive technologies to improve oocyte competence and support post-fertilization …

Conventional heterologous mitochondrial replacement therapy is clinically complicated by
“tri-parental” ethical concerns and limited source of healthy donor oocytes or zygotes …

Oocyte quality is one of the key factors affecting the outcome of ART. Therefore, how to
improve oocyte quality has become an urgent problem in the field of ART. In this study we …

In mammalian species, the mitochondrial genome is between 16.2 and 16.7 kb in size and
encodes key proteins associated with the cell's major energy-generating apparatus, the …