Phenibut: review and pharmacologic approaches to treating withdrawal

SR Penzak, M Bulloch - The Journal of Clinical Pharmacology, 2024 - Wiley Online Library
Abstract β‐Phenyl‐γ‐aminobutyric acid (phenibut) is an analog of the inhibitory
neurotransmitter γ‐aminobutyric acid (GABA) that was first synthesized in Russia in the early …

Safety and tolerability of the anxiolytic and nootropic drug phenibut: a systematic review of clinical trials and case reports

E Kupats, J Vrublevska, B Zvejniece… - …, 2020 - thieme-connect.com
Phenibut is a nootropic drug that exerts anxiolytic and antinociceptive effects by acting on
the GABA B receptor and the α 2-δ subunit of voltage-dependent calcium channels. An …

[HTML][HTML] ФУНКЦИОНАЛЬНЫЕ ЗАБОЛЕВАНИЯ ОРГАНОВ ПИЩЕВАРЕНИЯ. СИНДРОМЫ ПЕРЕКРЕСТА

ЛБ Лазебник, ЕВ Голованова, БА Волель… - Экспериментальная …, 2021 - cyberleninka.ru
Keywords: FUNCTIONAL DISEASES OF THE DIGESTIVE SYSTEM, FUNCTIONAL
HEARTBURN, FUNCTIONAL DYSPEPSIA, BILIARY DYSFUNCTION, IRRITABLE BOWEL …

When an obscurity becomes trend: social-media descriptions of tianeptine use and associated atypical drug use

KE Smith, JM Rogers, JC Strickland… - The American journal of …, 2021 - Taylor & Francis
Background: Originally believed to be an atypical antidepressant acting at serotonin
transporters, tianeptine is now known to also be an atypical agonist at mu-opioid receptors …

Phenibut (4‐amino‐3‐phenyl‐butyric acid): Availability, prevalence of use, desired effects and acute toxicity

DR Owen, DM Wood, JRH Archer… - Drug and alcohol …, 2016 - Wiley Online Library
Abstract Introduction and Aims There has been a global increase in the availability and use
of novel psychoactive substances (NPS) over the last decade. Phenibut (β‐phenyl‐γ …

Phenibut (β-phenyl-γ-aminobutyric acid): an easily obtainable “dietary supplement” with propensities for physical dependence and addiction

EA Jouney - Current psychiatry reports, 2019 - Springer
Abstract Purpose of Review Phenibut (β-phenyl-γ-aminobutyric acid) is a psychoactive
GABA analogue currently being marketed online as an anxiolytic and nootropic dietary …

Phenibut exposures and clinical effects reported to a regional poison center

DJ McCabe, SA Bangh, AM Arens, JB Cole - The American journal of …, 2019 - Elsevier
Background Phenibut is a synthetically produced central nervous system (CNS) depressant
that is structurally similar to the inhibitory neurotransmitter γ-aminobutyric acid (GABA) …

[HTML][HTML] Notes from the field: phenibut exposures reported to poison centers—United States, 2009–2019

JM Graves - MMWR. Morbidity and mortality weekly report, 2020 - cdc.gov
Phenibut (β-phenyl-γ-aminobutyric acid) is an unregulated* drug developed in Russia in the
1960s for use as an antianxiety medication with cognitive enhancement properties (1) …

Newly emerging drugs of abuse

K Tamama, MJ Lynch - Substance Use Disorders: From Etiology to …, 2020 - Springer
Drug use and the associated overdose deaths have been a serious public health threat in
the United States and the world. While traditional drugs of abuse such as cocaine remain …

Dissociative intoxication and prolonged withdrawal associated with phenibut: a case report

YB Joshi, SF Friend, B Jimenez… - Journal of clinical …, 2017 - journals.lww.com
To the Editors: Nootropic agents, or psychoactive sub-stances intended to augment or
enhance cognitive functioning, are becoming increasingly available through the internet …