Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling

J Jansen, BT van den Berge, M van den Broek… - …, 2022 - journals.biologists.com
Nephrotic syndrome (NS) is characterized by severe proteinuria as a consequence of kidney
glomerular injury due to podocyte damage. In vitro models mimicking in vivo podocyte …

Novel in vitro assays to detect circulating permeability factor(s) in idiopathic focal segmental glomerulosclerosis

DJW den Braanker, RJ Maas… - Nephrology Dialysis …, 2021 - academic.oup.com
Background Many patients with idiopathic focal segmental glomerulosclerosis (FSGS)
develop recurrence of proteinuria after kidney transplantation (TX). Although several …

Effects of tacrolimus on autophagy protein LC3 in puromycin-damaged mouse podocytes

X Yang, S Yu, L Yu, L Ge, Y Zhang… - Journal of …, 2020 - journals.sagepub.com
Objective To investigate the mechanism through which tacrolimus, often used to treat
refractory nephropathy, protects against puromycin-induced podocyte injury. Methods An in …

Sinkihwan-gamibang ameliorates puromycin aminonucleoside-induced nephrotic syndrome

HK Lee, YJ Jang, SW Na, HY Kim, BH Han… - Chinese Journal of …, 2022 - Elsevier
Nephrotic syndrome (NS) is a kidney disease characterized by hypertriglyceridemia,
massive proteinuria, hypo-albuminemia and peripheral edema. Sinkihwan-gamibang …

Protective role of cannabinoids against diabetic nephropathy induced in rats by streptozotocin

WX Fan, SJ Hong, T Wei, YN Yang, M Weng… - Tropical Journal of …, 2021 - ajol.info
Purpose: To investigate the effects of cannabinoid ligand in diabetic nephropathy mediated
by streptozotocin (STZ) injection in rats. Methods: Rats deprived of food were injected …

Die Rolle von Annexin A1 im Tiermodell der rasch progressiven Glomerulonephritis

R Labes - 2021 - depositonce.tu-berlin.de
Acute kidney disease like the anti-glomerular basement membrane disease (a-GBM-
disease) are serious diseases which may give rise to chronic kidney disease. The treatment …