Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

A significant proportion of recently approved drug molecules possess poor aqueous
solubility which further restrains their desired bioavailability. Poor aqueous solubility of these …

Poorly water‐soluble drug candidates are becoming more prevalent. It has been estimated
that approximately 60–70% of the drug molecules are insufficiently soluble in aqueous …

Sažetak Low oral bioavailability as a consequence of low water solubility of drugs is a
growing challenge to the development of new pharmaceutical products. One of the most …

Self-emulsifying drug delivery system (SEDDS) is an isotropic mixture of lipid, surfactant and
co-surfactant, which forms a fine emulsion when comes in contact of an aqueous medium …

Introduction: Lipid-based drug delivery systems (LBDDS) are the most promising technique
to formulate the poorly water soluble drugs. Nanotechnology strongly influences the …

Self-emulsifying drug delivery systems (SEDDS) offer potential for overcoming the inherent
slow dissolution and poor oral absorption of hydrophobic drugs by retaining them in a …

Poorly water-soluble drugs demonstrate significant challenge in pharmaceutical
development, which is linked to their limited oral bioavailability and therapeutic efficacy. To …

The main purpose of this study was to investigate the potential of self-nano-emulsifying drug
delivery system (SNEDDS) in improving the bioavailability of docetaxel (DCT) and its …

Introduction: Oral administration of a drug is the most common, ideal and preferred route of
administration. The main problem of oral drug formulations is their low bioavailability arises …