Atomic force microscopy as a tool for assessing the cellular elasticity and adhesiveness to identify cancer cells and tissues

J Zemła, J Danilkiewicz, B Orzechowska… - Seminars in cell & …, 2018 - Elsevier
From the first experiments of the atomic force microscopy (AFM) with biological samples, the
range of its potential applications grows extensively. One of them is the use of AFM to …

[HTML][HTML] Cancer cell mechanobiology: a new frontier for cancer research

W Yu, S Sharma, E Rao, AC Rowat… - Journal of the National …, 2022 - Elsevier
The study of physical and mechanical features of cancer cells, or cancer cell
mechanobiology, is a new frontier in cancer research. Such studies may enhance our …

Nano-mechanical signature of brain tumours

G Ciasca, TE Sassun, E Minelli, M Antonelli, M Papi… - Nanoscale, 2016 - pubs.rsc.org
Glioblastoma (GBM) and meningothelial meningioma (MM) are the most frequent malignant
and benign brain lesions, respectively. Mechanical cues play a major role in the progression …

Mapping viscoelastic properties of healthy and pathological red blood cells at the nanoscale level

G Ciasca, M Papi, S Di Claudio, M Chiarpotto… - Nanoscale, 2015 - pubs.rsc.org
In order to pass through the microcirculation, red blood cells (RBCs) need to undergo
extensive deformations and to recover the original shape. This extreme deformability is …

Curcumin-loaded graphene oxide flakes as an effective antibacterial system against methicillin-resistant Staphylococcus aureus

F Bugli, M Cacaci, V Palmieri, R Di Santo… - Interface …, 2018 - royalsocietypublishing.org
Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for serious hospital
infections worldwide and represents a global public health problem. Curcumin, the major …

Cancer cells optimize elasticity for efficient migration

AS Kashani, M Packirisamy - Royal Society Open …, 2020 - royalsocietypublishing.org
Cancer progression is associated with alternations in the cytoskeletal architecture of cells
and, consequently, their mechanical properties such as stiffness. Changing the mechanics …

Mechanical and structural comparison between primary tumor and lymph node metastasis cells in colorectal cancer

V Palmieri, D Lucchetti, A Maiorana, M Papi… - Soft matter, 2015 - pubs.rsc.org
SW480 and SW620 colon carcinoma cell lines derive from primary tumour and lymph-node
metastasis of the same patient, respectively. For this reason, these cells represent an ideal …

A fully-automated neural network analysis of AFM force-distance curves for cancer tissue diagnosis

E Minelli, G Ciasca, TE Sassun, M Antonelli… - Applied Physics …, 2017 - pubs.aip.org
Atomic Force Microscopy (AFM) has the unique capability of probing the nanoscale
mechanical properties of biological systems that affect and are affected by the occurrence of …

Biophysical properties of human breast cancer cells measured using silicon MEMS resonators and atomic force microscopy

EA Corbin, F Kong, CT Lim, WP King, R Bashir - Lab on a Chip, 2015 - pubs.rsc.org
Biophysical studies on individual cells can help to establish the relationship between
mechanics and biological function. In the case of cancer, mechanical properties of cells …

Two-stage machine learning models for bowel lesions characterisation using self-propelled capsule dynamics

KO Afebu, J Tian, E Papatheou, Y Liu, S Prasad - Nonlinear Dynamics, 2023 - Springer
To foster early bowel cancer diagnosis, a non-invasive biomechanical characterisation of
bowel lesions is proposed. This method uses the dynamics of a self-propelled capsule and a …