Gammaherpesviruses are an important class of oncogenic pathogens that are exquisitely
evolved to their respective hosts. As such, the human gammaherpesviruses Epstein-Barr …

Dendritic cells (DCs) link innate immune sensing of the environment to the initiation of
adaptive immune responses. Given their supreme capacity to interact with and present …

During unresolved infections, some viruses escape immunological control and establish a
persistant reservoir in certain cell types, such as human immunodeficiency virus (HIV), which …

Viruses transmit via the environmental and social interactions of their hosts. Herpesviruses
have colonized mammals since their earliest origins, suggesting that they exploit ancient …

Cytomegaloviruses (CMVs) establish chronic infections that spread from a primary entry site
to secondary vascular sites, such as the spleen, and then to tertiary shedding sites, such as …

Gamma-herpesviruses (γHVs) are widespread oncogenic pathogens that chronically infect
circulating lymphocytes. How they subvert the immune check-point function of the spleen to …

Lytic gammaherpesvirus infection restricts host gene expression by promoting widespread
degradation of cytoplasmic mRNA through the activity of the viral endonuclease SOX …

Herpesviruses are ubiquitous pathogens that cause much disease. The difficulty of clearing
their established infections makes host entry an important target for control. However, while …

Gamma-herpesviruses persist in lymphocytes and cause disease by driving their
proliferation. Lymphocyte infection is therefore a key pathogenetic event. Murid Herpesvirus …

Gammaherpesviruses (γHVs) are recognized as important pathogens in humans but their
relationship with other animal hosts, especially wildlife species, is less well characterized …