Highlights•Malaria caused by P. falciparum can result in chronic infections lasting
years.•Loss of surface antigen expression enables parasites to avoid immune …

Extensive research has examined why some people have frequent Plasmodium falciparum
malaria episodes in sub-Saharan Africa while others remain free of disease most of the time …

This study analyzed fifty years of severe malaria research worldwide. Malaria is a parasitic
disease that continues to have a significant impact on global health, particularly in sub …

Persistence of malaria parasites in asymptomatic hosts is crucial in areas of seasonally-
interrupted transmission, where P. falciparum bridges wet seasons months apart. During the …

The developmental decision made by malaria parasites to become sexual underlies all
malaria transmission. Here, we describe a rich atlas of short-and long-read single-cell …

Protein export and host membrane remodeling are crucial for multiple Plasmodium species
to establish a niche in infected hosts. To better understand the contribution of these …

Host iron deficiency is protective against severe malaria as the human malaria parasite
Plasmodium falciparum depends on bioavailable iron from its host to proliferate. The …

Abstract In Bandiagara, Mali, children experience on average two clinical malaria episodes
per year. However, even in the same transmission area, the number of uncomplicated …

Cerebral malaria (CM), the most lethal complication of Plasmodium falciparum severe
malaria (SM), remains fatal for 15–25% of affected children despite the availability of …

While often undetected and untreated, persistent seasonal asymptomatic malaria infections
remain a global public health problem. Despite the presence of parasites in the peripheral …