Histone methylation can occur at various sites in histone proteins, primarily on lysine and
arginine residues, and it can be governed by multiple positive and negative regulators, even …

Addition of chemical tags on the DNA and modification of histone proteins impart a distinct
feature on chromatin architecture. With the advancement in scientific research, the key …

Eight types of short-chain Lys acylations have recently been identified on histones:
propionylation, butyrylation, 2-hydroxyisobutyrylation, succinylation, malonylation …

Here, we provide an update of our review on homeobox genes that we wrote together with
Walter Gehring in 1994. Since then, comprehensive surveys of homeobox genes have …

Post-translational modifications (PTMs) of histones provide a fine-tuned mechanism for
regulating chromatin structure and dynamics. PTMs can alter direct interactions between …

Several mechanisms have been proposed for histone marks to exert their functions,
including altering the physical properties of nucleosomes by neutralization of charge via …

Post-translational modification of histones provides an important regulatory platform for
processes such as gene transcription and DNA damage repair. It has become increasingly …

The surface of nucleosomes is studded with a multiplicity of modifications. At least eight
different classes have been characterized to date and many different sites have been …

Polycomb group proteins have an essential role in the epigenetic maintenance of repressive
chromatin states. The gene-silencing activity of the Polycomb repressive complex 2 (PRC2) …

Protein lysine methylation is a distinct posttranslational modification that causes minimal
changes in the size and electrostatic status of lysine residues. Lysine methylation plays …