The ever-expanding myokinome: discovery challenges and therapeutic implications

M Whitham, MA Febbraio - Nature reviews Drug discovery, 2016 - nature.com
Exercise reduces the risk of a multitude of disorders, from metabolic disease to cancer, but
the molecular mechanisms mediating the protective effects of exercise are not completely …

Ion mobility spectrometry‐mass spectrometry (IMS‐MS) of small molecules: Separating and assigning structures to ions

C Lapthorn, F Pullen… - Mass spectrometry …, 2013 - Wiley Online Library
The phenomenon of ion mobility (IM), the movement/transport of charged particles under the
influence of an electric field, was first observed in the early 20th Century and harnessed later …

[图书][B] Ion mobility spectrometry

GA Eiceman, Z Karpas - 2005 - taylorfrancis.com
Key Developments for Faster, More Precise Detection Capabilities Driven by the demand for
the rapid and advanced detection of explosives, chemical and biological warfare agents …

[PDF][PDF] Wang

Y Wang - Jia Z, Yi Q, Song L. The various components implied …, 2018 - tranassoc.com
Systems and methods are disclosed for communicating data in an integrated sensor network
having one or more nodes coupled to an optical sensor network and a radio frequency …

Plasma Proteome Database as a resource for proteomics research: 2014 update

V Nanjappa, JK Thomas, A Marimuthu… - Nucleic acids …, 2014 - academic.oup.com
Abstract Plasma Proteome Database (PPD; http://www. plasmaproteomedatabase. org/) was
initially described in the year 2005 as a part of Human Proteome Organization's (HUPO's) …

Mining the plasma proteome for cancer biomarkers

SM Hanash, SJ Pitteri, VM Faca - Nature, 2008 - nature.com
Systematic searches for plasma proteins that are biological indicators, or biomarkers, for
cancer are underway. The difficulties caused by the complexity of biological-fluid proteomes …

Recent developments in liquid chromatography–mass spectrometry and related techniques

M Holčapek, R Jirásko, M Lísa - Journal of Chromatography A, 2012 - Elsevier
This review summarizes the state-of-art in liquid chromatography–mass spectrometry (LC–
MS) and related techniques with the main focus on recent developments in the last decade …

Ion mobility mass spectrometry of peptide ions: effects of drift gas and calibration strategies

MF Bush, IDG Campuzano, CV Robinson - Analytical chemistry, 2012 - ACS Publications
One difficulty in using ion mobility (IM) mass spectrometry (MS) to improve the specificity of
peptide ion assignments is that IM separations are performed using a range of pressures …

Gas-phase separation using a trapped ion mobility spectrometer

F Fernandez-Lima, DA Kaplan, J Suetering… - International Journal for …, 2011 - Springer
In the present work we describe the principles of operation, versatility and applicability of a
trapped ion mobility spectrometer (TIMS) analyzer for fast, gas-phase separation of …

Biomolecule analysis by ion mobility spectrometry

BC Bohrer, SI Merenbloom, SL Koeniger… - Annu. Rev. Anal …, 2008 - annualreviews.org
Although nonnative protein conformations, including intermediates along the folding
pathway and kinetically trapped misfolded species that disfavor the native state, are rarely …