The traditional gut‐centric view of coeliac disease is evolving as immune and genetic
insights underscore the central importance of a systemic, T cell immune response to gluten …

Background and Objective Coeliac disease (CD) is a common autoimmune disorder
triggered by gluten consumption in genetically predisposed individuals. CD is characterised …

Background There is potential for a paradigm shift from a biopsy‐to a serology‐based
diagnosis of coeliac disease in selected adult patients. However, it remains unknown if this …

Objective Potential coeliac disease (PCD) is characterised by positive serological and
genetic markers of coeliac disease with architecturally preserved duodenal mucosa. The …

The diagnosis of celiac disease (CD) is complex and requires a multi-step procedure
(symptoms, serology, duodenal biopsy, effect of a gluten-free diet, and optional genetic). The …

Objectives Diagnosis of coeliac disease based on serology only has been allowed since
2018 in Finland for adults meeting specific criteria. We studied the patient experiences and …

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Serum antibodies to the autoantigen transglutaminase 2 (TG2) are increasingly harnessed
to diagnose coeliac disease. Diagnostic guidelines for children give recommendation for a …

Background In uncertain cases of coeliac disease (CD), gluten challenge (GC) may be
necessary to confirm or exclude the diagnosis. However, data on diagnostic outcomes after …

Background Gastroenterologists still raise concerns about adopting a non-biopsy strategy
for diagnosing celiac disease (CeD) in adults. Aim To assess the performance of the …