Biophysical approaches for applying and measuring biological forces

W Sun, X Gao, H Lei, W Wang, Y Cao - Advanced Science, 2022 - Wiley Online Library
Over the past decades, increasing evidence has indicated that mechanical loads can
regulate the morphogenesis, proliferation, migration, and apoptosis of living cells …

[HTML][HTML] Machine learning opens a doorway for microrheology with optical tweezers in living systems

MG Smith, J Radford, E Febrianto, J Ramírez… - AIP Advances, 2023 - pubs.aip.org
It has been argued that linear microrheology with optical tweezers (MOT) of living systems
“is not an option” because of the wide gap between the observation time required to collect …

Micro-tensile rheology of fibrous gels quantifies strain-dependent anisotropy

S Goren, B Ergaz, D Barak, R Sorkin, A Lesman - Acta Biomaterialia, 2024 - Elsevier
Semiflexible fiber gels such as collagen and fibrin have unique nonlinear mechanical
properties that play an important role in tissue morphogenesis, wound healing, and cancer …

Optical Halo: A Proof of Concept for a New Broadband Microrheology Tool

J Ramírez, GM Gibson, M Tassieri - Micromachines, 2024 - pmc.ncbi.nlm.nih.gov
Microrheology, the study of material flow at micron scales, has advanced significantly since
Robert Brown's discovery of Brownian motion in 1827. Mason and Weitz's seminal work in …

OptoRheo: Simultaneous in situ micro-mechanical sensing and imaging of live 3D biological systems

T Mendonca, K Lis-Slimak, AB Matheson… - Communications …, 2023 - nature.com
Biomechanical cues from the extracellular matrix (ECM) are essential for directing many
cellular processes, from normal development and repair, to disease progression. To better …

Colloidal transport in twisted lattices of optical tweezers

NCX Stuhlmüller, TM Fischer, D de Las Heras - Physical Review E, 2022 - APS
We simulate the transport of colloidal particles driven by a static and homogeneous drift
force, and subject to the optical potential created by two lattices of optical tweezers. The …

Two ultracold highly magnetic atoms in a one-dimensional harmonic trap

M Suchorowski, A Dawid, M Tomza - Physical Review A, 2022 - APS
We theoretically investigate the properties of two interacting ultracold highly magnetic atoms
trapped in a one-dimensional harmonic potential. The atoms interact via an anisotropic long …

Fully angularly resolved 3D microrheology with optical tweezers

AB Matheson, T Mendonca, MG Smith, B Sutcliffe… - Rheologica Acta, 2024 - Springer
Microrheology with optical tweezers (MOT) is an all-optical technique that allows the user to
investigate a materials' viscoelastic properties at microscopic scales, and is particularly …

[HTML][HTML] An analytical framework for 3D microrheology measurements using an optical trap

AB Matheson, T Mendonca, M Smith, B Sutcliffe… - 2022 - europepmc.org
Microrheology with optical tweezers (MOT) is an all-optical technique that allows for
viscoelastic properties to be probed at microscopic scales, and is particularly useful for …

Broadband computational rheology for material characterisation

MG Smith - 2024 - theses.gla.ac.uk
Rheology is a wide-reaching field whose applications are underpinned by a prior
knowledge of the 'viscoelastic'properties of (complex) materials generally employed across …