With reference to reference genes: a systematic review of endogenous controls in gene expression studies

JR Chapman, J Waldenström - PloS one, 2015 - journals.plos.org
The choice of reference genes that are stably expressed amongst treatment groups is a
crucial step in real-time quantitative PCR gene expression studies. Recent guidelines have …

BDNF in sleep, insomnia, and sleep deprivation

K Schmitt, E Holsboer-Trachsler, A Eckert - Annals of medicine, 2016 - Taylor & Francis
The protein brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family
of growth factors involved in plasticity of neurons in several brain regions. There are …

The brain-derived neurotrophic factor: missing link between sleep deprivation, insomnia, and depression

M Rahmani, F Rahmani, N Rezaei - Neurochemical research, 2020 - Springer
The brain-derived neurotrophic factor (BDNF) mediates the plasticity-related changes that
associate with memory processing during sleep. Sleep deprivation and chronic stress are …

[HTML][HTML] Paradoxical sleep deprivation: neurochemical, hormonal and behavioral alterations. Evidence from 30 years of research

S Tufik, ML Andersen, LRA Bittencourt… - Anais da Academia …, 2009 - SciELO Brasil
Sleep comprises approximately one-third of a person's lifetime, but its impact on health and
medical conditions remains partially unrecognized. The prevalence of sleep disorders is …

[HTML][HTML] Intermittent hypoxia mediates cancer development and progression through HIF-1 and miRNA regulation

G Moriondo, P Soccio, M Minoves, G Scioscia… - Archivos de …, 2023 - Elsevier
Introduction There is still a debate for the link between obstructive sleep apnoea (OSA) and
cancer. The mechanisms underlying this causality are poorly understood. Several miRNAs …

[HTML][HTML] BDNF-TrkB signaling orchestrates the buildup process of local sleep

W ElGrawani, G Sun, FP Kliem, S Sennhauser… - Cell reports, 2024 - cell.com
Sleep debt accumulates during wakefulness, leading to increased slow wave activity (SWA)
during sleep, an encephalographic marker for sleep need. The use-dependent demands of …

Rapid antidepressant effects of sleep deprivation therapy correlates with serum BDNF changes in major depression

Y Gorgulu, O Caliyurt - Brain research bulletin, 2009 - Elsevier
Recent reports have suggested that brain-derived neurotrophic factor (BDNF) levels are
reduced in individuals suffering major depressive disorder and these levels normalize …

Dopamine transporter function fluctuates across sleep/wake state: potential impact for addiction

IP Alonso, JA Pino, S Kortagere, GE Torres… - …, 2021 - nature.com
The dopamine transporter (DAT) has been implicated in a variety of arousal-related
processes including the regulation of motor activity, learning, motivated behavior …

Identification of molecular signatures associated with sleep disorder and Alzheimer's disease

L Liang, J Yan, X Huang, C Zou, L Chen, R Li… - Frontiers in …, 2022 - frontiersin.org
Background Alzheimer's disease (AD) and sleep disorders are both neurodegenerative
conditions characterized by impaired or absent sleep. However, potential common …

Validation of housekeeping genes in the brains of rats submitted to chronic intermittent hypoxia, a sleep apnea model

GS Julian, RW de Oliveira, JC Perry, S Tufik… - PloS one, 2014 - journals.plos.org
Obstructive sleep apnea (OSA) is a syndrome characterized by intermittent nocturnal
hypoxia, sleep fragmentation, hypercapnia and respiratory effort, and it has been associated …