Recent progress in nanostructured smart drug delivery systems for cancer therapy: a review

MI Khan, MI Hossain, MK Hossain… - ACS Applied Bio …, 2022 - ACS Publications
Traditional treatment approaches for cancer involve intravenous chemotherapy or other
forms of drug delivery. These therapeutic measures suffer from several limitations such as …

Nanoparticles in drug delivery: From history to therapeutic applications

O Afzal, ASA Altamimi, MS Nadeem, SI Alzarea… - Nanomaterials, 2022 - mdpi.com
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

Targeting the transferrin receptor for brain drug delivery

KB Johnsen, A Burkhart, LB Thomsen… - Progress in …, 2019 - Elsevier
Obtaining efficient drug delivery to the brain remains the biggest challenge for the
development of therapeutics to treat diseases of the central nervous system. The main …

Multi-functional chitosan-based nanoparticles for drug delivery: Recent advanced insight into cancer therapy

B Tian, S Hua, J Liu - Carbohydrate Polymers, 2023 - Elsevier
Cancer therapy continues to be a major global concern, with conventional treatments
suffering from low efficacy, untargeted drug delivery, and severe side effects. Recent …

A review of chitosan in gene therapy: developments and challenges

L Dong, Y Li, H Cong, B Yu, Y Shen - Carbohydrate Polymers, 2024 - Elsevier
Gene therapy, as a revolutionary treatment, has been gaining more and more attention. The
key to gene therapy is the selection of suitable vectors for protection of exogenous nucleic …

Chitosan-g-estrone Nanoparticles of Palbociclib Vanished Hypoxic Breast Tumor after Targeted Delivery: Development and Ultrasound/Photoacoustic Imaging

AK Mehata, V Singh, Vikas, N Singh… - … Applied Materials & …, 2023 - ACS Publications
Breast cancer is the leading cause of death among women globally. Approximately 80% of
all breast cancers diagnosed are overexpressed with estrogen receptors (ERs). In this study …

The use of TPGS in drug delivery systems to overcome biological barriers

MT Luiz, LD Di Filippo, RC Alves, VHS Araújo… - European Polymer …, 2021 - Elsevier
Nanotechnology has been applied in the medicine field to improve the treatment of a wide
range of diseases. However, to reach the nanomedicines delivery to desirable target tissue …

Vitamin E TPGS-based nanomedicine, nanotheranostics, and targeted drug delivery: past, present, and future

AK Mehata, A Setia, AK Malik, R Hassani, HG Dailah… - Pharmaceutics, 2023 - mdpi.com
It has been seventy years since a water-soluble version of vitamin E called tocophersolan
(also known as TPGS) was produced; it was approved by USFDA in 1998 as an inactive …

Multifunctional polymeric nanoplatforms for brain diseases diagnosis, therapy and theranostics

S Shakeri, M Ashrafizadeh, A Zarrabi, R Roghanian… - Biomedicines, 2020 - mdpi.com
The blood–brain barrier (BBB) acts as a barrier to prevent the central nervous system (CNS)
from damage by substances that originate from the blood circulation. The BBB limits drug …

Targeted delivery of quercetin by nanoparticles based on chitosan sensitizing paclitaxel-resistant lung cancer cells to paclitaxel

Y Wang, H Yu, S Wang, C Gai, X Cui, Z Xu, W Li… - Materials Science and …, 2021 - Elsevier
Chemotherapy plays crucial roles in the clinical treatment of non-small cell lung cancer
(NSCLC). Nevertheless, acquired chemoresistance is a common and critical problem that …