Epilepsy in older people

A Sen, N Jette, M Husain, JW Sander - The Lancet, 2020 - thelancet.com
Globally, as populations age there will be challenges and opportunities to deliver optimal
health care to senior citizens. Epilepsy, a condition characterised by spontaneous recurrent …

Cerebrovascular reactivity measurement using magnetic resonance imaging: a systematic review

E Sleight, MS Stringer, I Marshall, JM Wardlaw… - Frontiers in …, 2021 - frontiersin.org
Cerebrovascular reactivity (CVR) magnetic resonance imaging (MRI) probes cerebral
haemodynamic changes in response to a vasodilatory stimulus. CVR closely relates to the …

Cognition and dementia in older patients with epilepsy

A Sen, V Capelli, M Husain - Brain, 2018 - academic.oup.com
With advances in healthcare and an ageing population, the number of older adults with
epilepsy is set to rise substantially across the world. In developed countries the highest …

Delayed seizures after intracerebral haemorrhage

A Biffi, A Rattani, CD Anderson, AM Ayres, EM Gurol… - Brain, 2016 - academic.oup.com
Late seizures after intracerebral haemorrhage occur after the initial acute haemorrhagic
insult subsides, and represent one of its most feared long-term sequelae. Both susceptibility …

Clinical, imaging, and biomarker evidence of amyloid-and tau-related neurodegeneration in late-onset epilepsy of unknown etiology

LB Hickman, JM Stern, DHS Silverman… - Frontiers in …, 2023 - frontiersin.org
Accumulating evidence suggests amyloid and tau-related neurodegeneration may play a
role in development of late-onset epilepsy of unknown etiology (LOEU). In this article, we …

Epilepsy and the risk of adverse cardiovascular events: A nationwide cohort study

J Mayer, AM Fawzy, A Bisson, M Pasi… - European Journal of …, 2024 - Wiley Online Library
Background and purpose Epilepsy is associated with higher morbidity and mortality
compared to people without epilepsy. We performed a retrospective cross‐sectional and …

Association between white matter hyperintensities, cortical volumes, and late-onset epilepsy

EL Johnson, GL Krauss, AK Lee, ALC Schneider… - Neurology, 2019 - AAN Enterprises
Objective To identify the association between brain vascular changes and cortical volumes
on MRI and late-onset epilepsy. Methods In 1993–1995, 1,920 participants (median age …

Late-onset unexplained epilepsy: what are we missing?

RA Sarkis, KC Willment, PB Pennell, G Marshall - Epilepsy & Behavior, 2019 - Elsevier
With the aging of the US population, the incidence of epilepsy will increase, with 25 to 50%
of new cases with no identifiable etiology diagnosed as late-onset unexplained epilepsy …

Seizures in the context of occult cerebrovascular disease

HCA Emsley, LM Parkes - Epilepsy & Behavior, 2020 - Elsevier
There is an important bidirectional relationship between seizures and cerebrovascular
disease (CVD). Aside from poststroke epilepsy, Occult CVD is an important cause of late …

Diagnosis and treatment of poststroke epilepsy: where do we stand?

M Mauritz, KN Poppert, E Trinka… - Current Treatment Options …, 2023 - Springer
Abstract Purpose of Review Stroke is the most common cause of seizures and epilepsy in
older adults. This educational paper aims to give an update on current clinical aspects of …