New trends in platinum and palladium complexes as antineoplastic agents

M Fanelli, M Formica, V Fusi, L Giorgi… - Coordination Chemistry …, 2016 - Elsevier
The discovery of cisplatin (cis-Pt (NH 3) 2 Cl 2) as an antineoplastic agent has focussed
attention on the rational design of metal complexes that can be potentially used in cancer …

A survey of the mechanisms of action of anticancer transition metal complexes

M Marloye, G Berger, M Gelbcke… - Future medicinal …, 2016 - Taylor & Francis
Metal complexes have been the subject of numerous investigations in oncology but, despite
the plethora of newly synthesized compounds, their precise mechanisms of action remain …

Michael addition-driven synthesis of cytotoxic palladium (ii) complexes from chromone thiosemicarbazones: investigation of anticancer activity through in vitro and in …

J Haribabu, N Balakrishnan, S Swaminathan… - New Journal of …, 2023 - pubs.rsc.org
Three Pd (II) complexes (1–3) containing tridentate chromone-based thiosemicarbazones
(SVSHL1–3) have been investigated as potential anticancer agents. The complexes of the …

Developing novel zinc (ii) and copper (ii) Schiff base complexes: combined experimental and theoretical investigation on their DNA/protein binding efficacy and …

M Das, S Mukherjee, B Koley, I Choudhuri… - New Journal of …, 2020 - pubs.rsc.org
Two new metal complexes, namely,[Zn2 (LH) 2 (N3) 4](1) and [Cu (L)(N3)](2), have been
derived from a Schiff base ligand,(E)-2-(((2-(piperidine-2-yl) ethyl) imino) methyl) phenol …

Synthesis, structures and mechanistic pathways of anticancer activity of palladium (II) complexes with indole-3-carbaldehyde thiosemicarbazones

J Haribabu, MM Tamizh, C Balachandran… - New Journal of …, 2018 - pubs.rsc.org
New PdII complexes of the types [PdCl (L)(PPh3)](1–5) and [Pd (L) 2](6 and 7)(HL= indole-3-
carbaldehyde thiosemicarbazones, HL1–HL5) have been synthesized in order to ascertain …

Heterodinuclear Ru–Pt complexes bridged with 2, 3-bis (pyridyl) pyrazinyl ligands: studies on kinetics, deoxyribonucleic acid/bovine serum albumin binding and …

R Bellam, D Jaganyi, RS Robinson - ACS omega, 2022 - ACS Publications
Di-and poly-homo/heteronuclear complexes have great potential as anticancer drugs. Here,
we report their reactivity, deoxyribonucleic acid (DNA)/bovine serum albumin (BSA) binding …

Investigation of DNA/BSA binding and cytotoxic properties of new Co (II), Ni (II) and Cu (II) hydrazone complexes

S Kanchanadevi, FR Fronczek, CI David… - Inorganica Chimica …, 2021 - Elsevier
Two mononuclear complexes of Co (II)(1) and Ni (II)(2) and a chloro bridged binuclear
copper (II) complex (3) of 2-benzoylpyridine-4-methoxybenzoylhydrazone have been …

Unveiling the catecholase activities and DNA binding interaction of mono-, di-, and polymeric Cu (ii) complexes derived from heterogeneous Schiff base ligands

R Maity, M Maity, K Jana, T Maity, N Sepay… - New Journal of …, 2023 - pubs.rsc.org
In this study, a comparative study of the catecholase activities and DNA binding of three Cu
(II) complexes is described. These complexes are mono-nuclear (1), di-nuclear (2), and poly …

Antitumor activity of tridentate pincer and related metal complexes

S Wu, Z Wu, Q Ge, X Zheng, Z Yang - Organic & Biomolecular …, 2021 - pubs.rsc.org
Pincer complexes featuring tunable tridentate ligand frameworks are one of the most actively
studied classes of metal-based complexes. Currently, growing attention is devoted to the …

An investigation on the DNA/protein binding, DNA cleavage and in vitro anticancer properties of SNO pincer type palladium (II) complexes with N-substituted isatin …

M Muralisankar, SM Basheer, J Haribabu… - Inorganica Chimica …, 2017 - Elsevier
Three pincer type palladium (II) complexes (1–3) were synthesised from the reactions of
PdCl 2 with thiosemicarbazone ligands (L1–L3), and characterized by elemental analyses …