The Role of the Toll-like Receptor 2 and the cGAS-STING Pathways in Breast Cancer: Friends or Foes?

C Cossu, A Di Lorenzo, I Fiorilla, AM Todesco… - International Journal of …, 2023 - mdpi.com
Breast cancer stands as a primary malignancy among women, ranking second in global
cancer-related deaths. Despite treatment advancements, many patients progress to …

Development of a broadly active influenza intranasal vaccine adjuvanted with self-assembled particles composed of mastoparan-7 and CpG

L Ontiveros-Padilla, CJ Batty, DA Hendy… - Frontiers in …, 2023 - frontiersin.org
Currently licensed vaccine adjuvants offer limited mucosal immunity, which is needed to
better combat respiratory infections such as influenza. Mast cells (MCs) are emerging as a …

NK cell marker gene-based model shows good predictive ability in prognosis and response to immunotherapies in hepatocellular carcinoma

J Li, Y Li, F Li, L Xu - Scientific Reports, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the fourth leading cause of malignancy worldwide, and
its progression is influenced by the immune microenvironment. Natural killer (NK) cells are …

Polymeric cGAMP microparticles affect the immunogenicity of a broadly active influenza mRNA lipid nanoparticle vaccine

DA Hendy, Y Ma, TA Dixon, CT Murphy… - Journal of Controlled …, 2024 - Elsevier
Influenza outbreaks are a major burden worldwide annually. While seasonal vaccines do
provide protection against infection, they are limited in that they need to be updated every …

Natural killer cell regulation of breast cancer stem cells mediates metastatic dormancy

GG Bushnell, D Sharma, HC Wilmot, M Zheng… - Cancer …, 2024 - aacrjournals.org
Breast cancer patients with estrogen receptor positive tumors face a constant risk of disease
recurrence for the remainder of their lives. Dormant tumor cells residing in tissues such as …