The cancer is a serious health problem, which is The cancer death rate (cancer mortality) is
158.3 per 100,000 men and women per year (based on 2013–2017 deaths). Both clinical …

Glioblastoma (GBM) is the most common malignant brain tumor in adults, and
immunotherapies and genetic therapies for GBM have evolved dramatically over the past …

Integrated bioinformatics and statistical approaches are now playing the vital role in
identifying potential molecular biomarkers more accurately in presence of huge number of …

Digestive system diseases remain a formidable challenge to human health. NOD-like
receptor family pyrin domain containing 3 (NLRP3) inflammasome is the most characteristic …

NLR family pyrin domain containing 3 (NLRP3) inflammasome formation is triggered by the
damaged mitochondria releasing reactive oxygen species. Doxycycline was shown to …

Ubiquitination, a pivotal posttranslational modification of proteins, plays a fundamental role
in regulating protein stability. The dysregulation of ubiquitinating and deubiquitinating …

The NLR family pyrin domain containing 3 (NLRP3) promotes the growth of colorectal
cancer (CRC). However, the therapeutic effect of NLRP3 inhibition on CRC cell progression …

Context Ulcerative colitis (UC) is a common acute or chronic intestinal disease with an
imbalance of inflammation. Picroside II (P-II) exerts a protective role in various inflammation …

The functions of mitochondria, including energy production and biomolecule synthesis, have
been known for a long time. Given the rising incidence of cancer, the role of mitochondria in …

Prostate cancer is a male malignant tumor disease with high incidence and mortality. This
study was designed to explore the effects of ulinastatin (UTI) on the malignant progression of …