Publisher Summary CD44 is a ubiquitous multistructural and multifunctional cell surface
adhesion molecule involved in cell–cell and cell–matrix interactions. CD44s is a single …

The CD44 proteins form a ubiquitously expressed family of cell surface adhesion molecules
involved in cell-cell and cell-matrix interactions. The multiple protein isoforms are encoded …

CD44 is a multistructural and multifunctional cell surface molecule involved in cell
proliferation, cell differentiation, cell migration, angiogenesis, presentation of cytokines …

The neurofibromatosis-2 (NF2) gene encodes merlin, an ezrin-radixin-moesin-(ERM)-
related protein that functions as a tumor suppressor. We found that merlin mediates contact …

Current therapies for chronic inflammatory diseases typically act through the nonspecific
downregulation of immune cell activation. However, it is becoming increasingly evident that …

Background: CD44 is widely used as a putative cancer stem cells (CSCs) marker for
colorectal cancer (CRC). However, the prognostic role of CD44 in CRC remains …

CD44 was once thought to simply be a transmembrane adhesion molecule that also played
a role in the metabolism of its principal ligand hyaluronan. Investigations of CD44 over the …

The multistep model of leukocyte recruitment to sites of inflammation has helped elucidate
specific molecular cues for each of the individual steps. However, it is less clear how cells …

Although CD44 is expressed on a wide variety of cell types, few of them use it to recognize
the ligand hyaluronan (HA). A glycosylation-defective clone of Chinese hamster ovary cells …

To understand how the hyaluronan receptor CD44 regulates tumor metastasis, the murine
mammary carcinoma TA3/St, which constitutively expresses cell surface CD44, was …