Health-related toxicity of emerging per-and polyfluoroalkyl substances: Comparison to legacy PFOS and PFOA
Per-and polyfluoroalkyl substances (PFAS) are highly persistent, manufactured chemicals
used in various manufacturing processes and found in numerous commercial products. With …
used in various manufacturing processes and found in numerous commercial products. With …
Obesity II: establishing causal links between chemical exposures and obesity
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …
prevailing view is that obesity results from an imbalance between energy intake and …
[HTML][HTML] Exposure to a mixture of legacy, alternative, and replacement per-and polyfluoroalkyl substances (PFAS) results in sex-dependent modulation of cholesterol …
Background Epidemiological studies have shown Per-and polyfluoroalkyl substances
(PFAS) to be associated with diseases of dysregulated lipid and sterol homeostasis such as …
(PFAS) to be associated with diseases of dysregulated lipid and sterol homeostasis such as …
[HTML][HTML] Per-and polyfluoroalkyl substance (PFAS) exposure, maternal metabolomic perturbation, and fetal growth in African American women: A meet-in-the-middle …
Background Prenatal exposures to per-and polyfluoroalkyl substances (PFAS) have been
linked to reduced fetal growth. However, the detailed molecular mechanisms remain largely …
linked to reduced fetal growth. However, the detailed molecular mechanisms remain largely …
[HTML][HTML] Non-targeted metabolomics and associations with per-and polyfluoroalkyl substances (PFAS) exposure in humans: A scoping review
Objective To summarize the application of non-targeted metabolomics in epidemiological
studies that assessed metabolite and metabolic pathway alterations associated with per-and …
studies that assessed metabolite and metabolic pathway alterations associated with per-and …
Perfluoroalkyl substances and lipid concentrations in the blood: A systematic review of epidemiological studies
SH Ho, SXH Soh, MX Wang, J Ong, A Seah… - Science of The Total …, 2022 - Elsevier
Background Perfluoroalkyl substances (PFAS) are widely used synthetic aliphatic
compounds. This systematic review aims to assess PFAS associations with low-density …
compounds. This systematic review aims to assess PFAS associations with low-density …
[HTML][HTML] Association of per-and polyfluoroalkyl substance exposure with fatty liver disease risk in US adults
Background & Aims Per-and polyfluoroalkyl substances (PFAS) are widespread pollutants
with demonstrated hepatotoxicity. Few studies have examined the association between …
with demonstrated hepatotoxicity. Few studies have examined the association between …
Associations between per-and polyfluoroalkyl substances exposures and blood lipid levels among adults—a meta-analysis
Background: Associations between per-and polyfluoroalkyl substances (PFAS) and blood
lipid levels in humans were mixed. Objectives: The objective of this meta-analysis was to …
lipid levels in humans were mixed. Objectives: The objective of this meta-analysis was to …
[HTML][HTML] Changes in plasma levels of per-and polyfluoroalkyl substances (PFAS) are associated with changes in plasma lipids-A longitudinal study over 10 years
L Dunder, PM Lind, S Salihovic, J Stubleski… - Environmental …, 2022 - Elsevier
Background Associations between per-and polyfluoroalkyl substances (PFAS), mainly PFOS
and PFOA, and increased blood lipids have been reported primarily from cross-sectional …
and PFOA, and increased blood lipids have been reported primarily from cross-sectional …
Metabolic signatures of youth exposure to mixtures of per-and polyfluoroalkyl substances: a multi-cohort study
Background: Exposure to per-and polyfluoroalkyl substances (PFAS) is ubiquitous and has
been associated with an increased risk of several cardiometabolic diseases. However, the …
been associated with an increased risk of several cardiometabolic diseases. However, the …