Detection of toxins involved in foodborne diseases caused by Gram‐positive bacteria

A Rajkovic, J Jovanovic, S Monteiro… - … reviews in food …, 2020 - Wiley Online Library
Bacterial toxins are food safety hazards causing about 10% of all reported foodborne
outbreaks in Europe. Pertinent to Gram‐positive pathogens, the most relevant toxins are …

Botulinum toxin: bioweapon & magic drug

RK Dhaked, MK Singh, P Singh… - Indian Journal of Medical …, 2010 - journals.lww.com
Botulinum neurotoxins, causative agents of botulism in humans, are produced by
Clostridium botulinum, an anaerobic spore-former Gram positive bacillus. Botulinum …

Multiplex biosensing based on highly sensitive magnetic nanolabel quantification: rapid detection of botulinum neurotoxins A, B, and E in liquids

AV Orlov, SL Znoyko, VR Cherkasov… - Analytical …, 2016 - ACS Publications
We present a multiplex quantitative lateral flow (LF) assay for simultaneous on-site detection
of botulinum neurotoxin (BoNT) types A, B, and E in complex matrixes, which is innovative …

Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay

E Fernandez-Salas, J Wang, Y Molina, JB Nelson… - PLoS …, 2012 - journals.plos.org
Botulinum neurotoxin serotype A (BoNT/A), a potent therapeutic used to treat various
disorders, inhibits vesicular neurotransmitter exocytosis by cleaving SNAP25. Development …

Proteomic methods of detection and quantification of protein toxins

M Duracova, J Klimentova, A Fucikova, J Dresler - Toxins, 2018 - mdpi.com
Biological toxins are a heterogeneous group of compounds that share commonalities with
biological and chemical agents. Among them, protein toxins represent a considerable …

Botulism Diagnostics: From Clinical Symptoms to in vitro Assays

S Cai, BR Singh, S Sharma - Critical reviews in microbiology, 2007 - Taylor & Francis
Botulinum neurotoxin (BoNT), which cause the deadly neuroparalytic disease, botulism, is
the most toxic substance known to man. BoNT can be used as potential bioterrorism agents …

Recent advances in the detection of food toxins using mass spectrometry

V Ahuja, A Singh, D Paul, D Dasgupta… - Chemical Research …, 2023 - ACS Publications
Edibles are the only source of nutrients and energy for humans. However, ingredients of
edibles have undergone many physicochemical changes during preparation and storage …

Clostridium botulinum type C, D, C/D, and D/C: An update

F Meurens, F Carlin, M Federighi, ME Filippitzi… - Frontiers in …, 2023 - frontiersin.org
Clostridium botulinum is the main causative agent of botulism, a neurological disease
encountered in humans as well as animals. Nine types of botulinum neurotoxins (BoNTs) …

Attomolar detection of botulinum toxin type A in complex biological matrices

K Bagramyan, JR Barash, SS Arnon, M Kalkum - PloS one, 2008 - journals.plos.org
Background A highly sensitive, rapid and cost efficient method that can detect active
botulinum neurotoxin (BoNT) in complex biological samples such as foods or serum is …

Sensing the deadliest toxin: technologies for botulinum neurotoxin detection

P Čapek, TJ Dickerson - Toxins, 2010 - mdpi.com
Sensitive and rapid detection of botulinum neurotoxins (BoNTs), the most poisonous
substances known to date, is essential for studies of medical applications of BoNTs and …