Extrahepatic morbidity and mortality of chronic hepatitis C

F Negro, D Forton, A Craxì, MS Sulkowski, JJ Feld… - Gastroenterology, 2015 - Elsevier
Chronic hepatitis C virus (HCV) infection is associated with several extrahepatic
manifestations. Patients with HCV may develop mixed cryoglobulinemia and its sequelae …

[HTML][HTML] Epidemiology and natural history of hepatitis C virus infection

MH Lee, HI Yang, Y Yuan, G L'Italien… - World journal of …, 2014 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) affects 130-210 million people worldwide and is one of the major
risk factors for hepatocellular carcinoma. Globally, at least one third of hepatocellular …

[PDF][PDF] Hepatitis C guidance 2019 update: American Association for the Study of Liver Diseases–Infectious Diseases Society of America recommendations for testing …

MG Ghany, TR Morgan… - …, 2020 - Wiley Online Library
HCV infection, risk-based screening failed to identify the majority of individuals with HCV
infection due to both clinician and patient barriers.(9-12) Analysis of the 2003-2010 National …

[HTML][HTML] The natural history of hepatitis C virus (HCV) infection

SL Chen, TR Morgan - International journal of medical sciences, 2006 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) is a leading cause of chronic liver disease, cirrhosis, and
hepatocellular carcinoma, as well as the most common indication for liver transplantation in …

Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis

R Moucari, T Asselah, D Cazals–Hatem, H Voitot… - Gastroenterology, 2008 - Elsevier
BACKGROUND & AIMS: Our study was designed to test the association between insulin
resistance (IR) and hepatitis C virus (HCV) genotypes using serum HCV RNA level and liver …

[HTML][HTML] Facts and fictions of HCV and comorbidities: steatosis, diabetes mellitus, and cardiovascular diseases

F Negro - Journal of hepatology, 2014 - Elsevier
The hepatitis C virus (HCV) is a major cause of chronic hepatitis, cirrhosis and
hepatocellular carcinoma worldwide. A significant portion of the morbidity and mortality …

[HTML][HTML] Diabetes mellitus, insulin resistance and hepatitis C virus infection: A contemporary review

AC Desbois, P Cacoub - World journal of gastroenterology, 2017 - ncbi.nlm.nih.gov
AIM To summarise the literature data on hepatitis C virus (HCV)-infected patients concerning
the prevalence of glucose abnormalities and associated risk. METHODS We conducted a …

The evolving role of leptin and adiponectin in chronic liver diseases

E Tsochatzis, GV Papatheodoridis… - Official journal of the …, 2006 - journals.lww.com
Leptin and adiponectin, the main metabolic products of adipose tissue, have been
implicated in a wide spectrum of human diseases. Given the frequent presence of hepatic …

[HTML][HTML] Fatty liver is associated with an increased risk of diabetes and cardiovascular disease-Evidence from three different disease models: NAFLD, HCV and HIV

A Lonardo, S Ballestri, G Guaraldi… - World journal of …, 2016 - ncbi.nlm.nih.gov
Fatty liver, which frequently coexists with necro-inflammatory and fibrotic changes, may
occur in the setting of nonalcoholic fatty liver disease (NAFLD) and chronic infections due to …

[PDF][PDF] The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype‐specific mechanisms

V Pazienza, S Clément, P Pugnale, S Conzelman… - …, 2007 - Wiley Online Library
Both molecular and clinical evidence support a link between HCV infection and insulin
resistance. We examined the in vitro interaction between the HCV core protein of genotypes …