Recent advances in biosensor for detection of lung cancer biomarkers

G Yang, Z Xiao, C Tang, Y Deng, H Huang… - Biosensors and …, 2019 - Elsevier
Lung cancer is primary cancer threatening human life worldwide with the highest mortality
rate. The early detection of lung cancer plays a critical role in the early diagnosis and …

DNA methylation biomarkers: cancer and beyond

T Mikeska, JM Craig - Genes, 2014 - mdpi.com
Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …

The role of liquid biopsy in early diagnosis of lung cancer

C Freitas, C Sousa, F Machado, M Serino… - Frontiers in …, 2021 - frontiersin.org
Liquid biopsy is an emerging technology with a potential role in the screening and early
detection of lung cancer. Several liquid biopsy-derived biomarkers have been identified and …

Molecular pathology of primary non-small cell lung cancer

DI Suster, M Mino-Kenudson - Archives of medical research, 2020 - Elsevier
Lung carcinoma is one of the most common human cancers and is estimated to have an
incidence of approximately 2 million new cases per year worldwide with a 20% mortality …

Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook

E Lianidou - Molecular Oncology, 2021 - Wiley Online Library
Liquid biopsy, a minimally invasive approach, is a highly powerful clinical tool for the real‐
time follow‐up of cancer and overcomes many limitations of tissue biopsies. Epigenetic …

[HTML][HTML] Epigenetics in non-small cell lung cancer: from basics to therapeutics

J Ansari, RE Shackelford, H El-Osta - Translational lung cancer …, 2016 - ncbi.nlm.nih.gov
Lung cancer remains the number one cause of cancer-related deaths worldwide with
221,200 estimated new cases and 158,040 estimated deaths in 2015. Approximately 80% of …

Blood-based liquid biopsy: Insights into early detection and clinical management of lung cancer

C Liu, X Xiang, S Han, HY Lim, L Li, X Zhang, Z Ma… - Cancer Letters, 2022 - Elsevier
Currently, early detection of lung cancer relies on the characterisation of images generated
from computed tomography (CT). However, lung tissue biopsy, a highly invasive surgical …

Epigenetics in lung cancer diagnosis and therapy

A Mehta, S Dobersch, AJ Romero-Olmedo… - Cancer and Metastasis …, 2015 - Springer
Lung cancer is the leading cause of cancer-related deaths worldwide. The initiation and
progression of lung cancer is the result of the interaction between permanent genetic and …

Artificial light at night: melatonin as a mediator between the environment and epigenome

A Haim, AE Zubidat - … Transactions of the Royal Society B …, 2015 - royalsocietypublishing.org
The adverse effects of excessive use of artificial light at night (ALAN) are becoming
increasingly evident and associated with several health problems including cancer. Results …

Smoking-associated DNA methylation markers predict lung cancer incidence

Y Zhang, M Elgizouli, B Schöttker, B Holleczek… - Clinical …, 2016 - Springer
Background Newly established blood DNA methylation markers that are strongly associated
with smoking might open new avenues for lung cancer (LC) screening. We aimed to assess …