Important flavonoids and their role as a therapeutic agent

A Ullah, S Munir, SL Badshah, N Khan, L Ghani… - Molecules, 2020 - mdpi.com
Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and
leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of …

The Characteristic of Virulence, Biofilm and Antibiotic Resistance of Klebsiella pneumoniae

G Wang, G Zhao, X Chao, L Xie, H Wang - International journal of …, 2020 - mdpi.com
Klebsiella pneumoniae is an important gram-negative opportunistic pathogen that causes a
variety of infectious diseases, including urinary tract infections, bacteremia, pneumonia, and …

Klebsiella pneumoniae: a major worldwide source and shuttle for antibiotic resistance

S Navon-Venezia, K Kondratyeva… - FEMS microbiology …, 2017 - academic.oup.com
Klebsiella pneumoniae is an important multidrug-resistant (MDR) pathogen affecting
humans and a major source for hospital infections associated with high morbidity and …

Biological effects of quinolones: a family of broad-spectrum antimicrobial agents

AR Millanao, AY Mora, NA Villagra, SA Bucarey… - Molecules, 2021 - mdpi.com
Broad antibacterial spectrum, high oral bioavailability and excellent tissue penetration
combined with safety and few, yet rare, unwanted effects, have made the quinolones class of …

Delivery of antibacterial agents for wound healing applications using polysaccharide-based scaffolds

H Nosrati, M Heydari, Z Tootiaei, S Ganjbar… - Journal of Drug Delivery …, 2023 - Elsevier
Skin is the first line of defense against pathogenic microorganisms. Any serious damage to
this organ can lead to bacterial invasion and wound infection. Such infections can cause not …

Hydrazone comprising compounds as promising anti-infective agents: Chemistry and structure-property relationship

PC Sharma, D Sharma, A Sharma, N Saini… - Materials Today …, 2020 - Elsevier
Despite the adverse effects of microbial hazards on public health, major pharmaceutical
firms have left the field of anti-infective development and a dramatic reduction in the number …

Recent advances in the synthetic and medicinal perspective of quinolones: A review

P Dhiman, N Arora, PV Thanikachalam, V Monga - Bioorganic Chemistry, 2019 - Elsevier
In the modern scenario, the quinolone scaffold has emerged as a very potent motif
considering its clinical significance. Quinolones possess wide range of pharmacological …

Engineered Janus amphipathic polymeric fiber films with unidirectional drainage and anti-adhesion abilities to accelerate wound healing

Z Luo, L Jiang, C Xu, D Kai, X Fan, M You… - Chemical Engineering …, 2021 - Elsevier
Rational design of new wound dressing materials aims to accelerate wound healing.
Traditional hydrophilic wound dressings, however, tend to cause retention of wound exudate …

Membrane active 7-thiazoxime quinolones as novel DNA binding agents to decrease the genes expression and exert potent anti-methicillin-resistant Staphylococcus …

JP Chen, N Battini, MF Ansari, CH Zhou - European Journal of Medicinal …, 2021 - Elsevier
A novel class of 7-thiazoxime quinolones was developed as potential antimicrobial agents
for the sake of bypassing resistance of quinolones. Biological assays revealed that some …

Photodegradation for different dissociated species of norfloxacin and ofloxacin in water ice under solar irradiation

Z Li, J Zhang, D Dong, L Zhang, H Sun, Y Wang… - Journal of Hazardous …, 2024 - Elsevier
Ice is an important medium that regulates the transformation of organic contaminants.
Nonetheless, photodegradation of emerging fluoroquinolone (FQ) antibiotics in the ice …