Highlights This review focuses on the therapeutic mechanisms, targeting strategies of
various nanomaterials in acute liver failure, and recent advances of diverse nanomaterials …

Yeast has been employed as an effective derived drug carrier as a unicellular
microorganism. Many research works have been devoted to the encapsulation of nucleic …

Recent advances in tumor immunotherapy mainly tend to remodel the immunosuppressive
tumor microenvironment (TME) for immune enhancement. However, the complexity of TME …

Sonic hedgehog (SHH) and heat shock protein 90β (HSP90β) have been implicated in
nonalcoholic steatohepatitis (NASH) but their molecular mechanisms of action remain …

Myocardial ischemia reperfusion (IR) injury is closely related to the overwhelming
inflammation in the myocardium. Herein, cardiomyocyte-targeted nanotherapeutics were …

Antibody-based therapeutics, which induce apoptosis of malignant cells by selectively
binding to their receptors, hold tremendous promise for clinical cancer therapy. Tumor …

Exogenous insulin (INS) is critical for managing diabetes. However, owing to its short in vivo
half-life, frequent injection of INS is un-avoidable, which is both painful and inconvenient …

Cancer phenotypic lethality targets a nonessential enzyme in normal cells that is required for
cancer survival, which can overcome the problem of the high degree of intra-tumor …

This research focused on health management through the identification of suitable
interventions in stressed livestock. For this investigation, we conducted two experiments …