Selenium nanoparticles: A potent chemotherapeutic agent and an elucidation of its mechanism

S Menon, SD Ks, R Santhiya, S Rajeshkumar… - Colloids and Surfaces B …, 2018 - Elsevier
Selenium nanoparticles have at present picked up a vital prospect in the field of medicine,
due to their inquisitive properties when compared to other selenium compounds. They are …

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

LR Ferguson, H Chen, AR Collins, M Connell… - Seminars in cancer …, 2015 - Elsevier
Genomic instability can initiate cancer, augment progression, and influence the overall
prognosis of the affected patient. Genomic instability arises from many different pathways …

Selenium, selenoproteins and neurodegenerative diseases

BR Cardoso, BR Roberts, AI Bush, DJ Hare - Metallomics, 2015 - academic.oup.com
It is unsurprising that our understanding of the role of selenium in neurological function is
somewhat immature, considering its relatively recent discovery as an essential element to …

Structural features of microbial exopolysaccharides in relation to their antioxidant activity

M Andrew, G Jayaraman - Carbohydrate research, 2020 - Elsevier
Oxidative damage caused by free radicals is an inevitable and pervasive phenomenon that
leads to cell damage and the emergence of diseases including ageing, cancer, diabetes …

Selenium, aging and aging-related diseases

Z Cai, J Zhang, H Li - Aging clinical and experimental research, 2019 - Springer
Selenium is an essential trace element in the human body and plays an important role in the
body via selenoprotein, which contains selenium. Selenoproteins (glutathione peroxidase …

Protection of cisplatin-induced spermatotoxicity, DNA damage and chromatin abnormality by selenium nano-particles

MA Rezvanfar, MA Rezvanfar, AR Shahverdi… - Toxicology and applied …, 2013 - Elsevier
Cisplatin (CIS), an anticancer alkylating agent, induces DNA adducts and effectively cross
links the DNA strands and so affects spermatozoa as a male reproductive toxicant. The …

Impact of selenium on biomarkers and clinical aspects related to ageing. A review

U Alehagen, TB Opstad, J Alexander, A Larsson… - Biomolecules, 2021 - mdpi.com
Selenium (Se) is an essential dietary trace element that plays an important role in the
prevention of inflammation, cardiovascular diseases, infections, and cancer. Selenoproteins …

[HTML][HTML] tRNA modifications regulate translation during cellular stress

C Gu, TJ Begley, PC Dedon - FEBS letters, 2014 - Elsevier
The regulation of gene expression in response to stress is an essential cellular protection
mechanism. Recent advances in tRNA modification analysis and genome-based codon bias …

Effects of chitosan-stabilized selenium nanoparticles on cell proliferation, apoptosis and cell cycle pattern in HepG2 cells: comparison with other selenospecies

H Estevez, JC Garcia-Lidon, JL Luque-Garcia… - Colloids and Surfaces B …, 2014 - Elsevier
Selenium is an essential element that plays an important role in many biological functions.
Many studies have reported the potential beneficial effects of Se intake for cancer therapy …

Ameliorative effect of selenium nanoparticles on testicular toxicity induced by cisplatin in adult male rats

AT Keshta, AM Fathallah, YA Attia, EA Salem… - Food and Chemical …, 2023 - Elsevier
Cisplatin (Cis) is a treatment for testicular germ-cell tumors (TGCTs). Unfortunately, it causes
testicular toxicity due to releasing reactive oxygen species (ROS) causing damage to …