Adolescence encompasses a sensitive developmental period of enhanced clinical
vulnerability to nicotine, tobacco, and e‐cigarettes. While there are sociocultural influences …

Adolescent brain maturation is characterized by the emergence of executive function
mediated by the prefrontal cortex, eg, goal planning, inhibition of impulsive behavior and set …

Relapse to cocaine use after prolonged abstinence is an important clinical problem. This
relapse is often induced by exposure to cues associated with cocaine use. To account for …

Given the rise in teenage use of electronic nicotine delivery systems (“vaping”) in
congruence with the increasing numbers of drug-related emergencies, it is critical to expand …

Adolescence represents a key period of brain development underpinned by the ongoing
maturation of the prefrontal cortex—a brain region involved in the regulation of behaviour …

Traditionally, animal models of schizophrenia were predominantly pharmacological
constructs focused on phenomena linked to dopamine and glutamate neurotransmitter …

Prefrontal cortex (PFC) mediates an assortment of cognitive functions including working
memory, behavioral flexibility, attention, and future planning. Unlike the hippocampus …

There is recent evidence of continuing development throughout adolescence in two neural
areas involved in emotion and cognition, the basolateral amygdala (BLN) and the medial …

Abnormal development can lead to deficits in adult brain function, a trajectory likely
underlying adolescent-onset psychiatric conditions such as schizophrenia. Developmental …

Adolescence is a crucial developmental period characterized by specific behaviors
reflecting the immaturity of decision-making abilities. However, the maturation of precise …