Mechanism of action of aspartate aminotransferase proposed on the basis of its spatial structure
JF Kirsch, G Eichele, GC Ford, MG Vincent… - Journal of molecular …, 1984 - Elsevier
Aspartate aminotransferase is a pyridoxal phosphate-dependent enzyme that catalyses the
transamination reaction: l-aspartate+ 2-oxoglutarate⇋ oxaloacetate+ l-glutamate. The …
transamination reaction: l-aspartate+ 2-oxoglutarate⇋ oxaloacetate+ l-glutamate. The …
Tautomerism in pyridoxal phosphate and in enzymatic catalysis
DE Metzler - Advances in enzymology and related areas of …, 1979 - books.google.com
The rapid equilibration of isomers in which one or more hydrogen atoms change positions is
a prevalent phenomenon among biochemical substances. Although it has been suggested …
a prevalent phenomenon among biochemical substances. Although it has been suggested …
Stereochemistry of pyridoxal phosphate catalyzed enzyme reactions
JC Vederas, HG Floss - Accounts of Chemical Research, 1980 - ACS Publications
All living organisms use pyridoxal phosphate (PLP), the biochemically functional derivative
of vitamin B6, to synthesize, degrade, and interconvert amino acids. In the presence of the …
of vitamin B6, to synthesize, degrade, and interconvert amino acids. In the presence of the …
Stereospecificity of sodium borohydride reduction of tyrosine decarboxylase from Streptococcus faecalis.
JC Vederas, ID Reingold, HW Sellers - Journal of Biological Chemistry, 1979 - ASBMB
Sodium boro [3H] hydride reduction of tyrosine decarboxylase from Streptococcus faecalis
followed by complete hydrolysis of the enzyme produces epsilon-[3H] pyridoxyllysine …
followed by complete hydrolysis of the enzyme produces epsilon-[3H] pyridoxyllysine …
Stereochemistry of metabolic reactions of amino acids
DW Young - Topics in Stereochemistry, 1994 - Wiley Online Library
Stereochemistry of metabolic reactions of amino acids Page 390 Stereochemistry of Metabolic
Reactions of Amino Acids DOUGLAS W. YOUNG School of Chemistry and Molecular Sciences …
Reactions of Amino Acids DOUGLAS W. YOUNG School of Chemistry and Molecular Sciences …
Interaction of a 5-trans-vinylcarboxylic acid analogue of pyridoxal 5'-phosphate with apoaspartate aminotransferase. Covalent labeling of the enzyme
R Miura, DE Metzler - Biochemistry, 1976 - ACS Publications
Retsu Miura* and David E. Metzler* abstract: The S-Zrtm-vinylcarboxylic acid analogue of
pyridoxal 5'-phosphate has been prepared. Its pAfa values were determined as 3.08, 4.10 …
pyridoxal 5'-phosphate has been prepared. Its pAfa values were determined as 3.08, 4.10 …
Stereochemical constraint in the evolution of pyridoxal‐5′‐phosphate‐DApenDAnt enzymes. A hypothesis
P Christen, P Kasper, H Gehring, M Sterk - FEBS letters, 1996 - Wiley Online Library
In the transamination reactions undergone by pyridoxal‐5′‐phosphate‐DApenDAnt
enzymes that act on l‐amino acids, the C4′ atom of the cofactor is without exception …
enzymes that act on l‐amino acids, the C4′ atom of the cofactor is without exception …
Stereochemistry of pyridoxal phosphate-catalyzed reactions
HG Floss, JC Vederas - New Comprehensive Biochemistry, 1982 - Elsevier
Publisher Summary In devising its synthetic strategies Nature has developed a number of
molecules, enzyme substrates or cofactors, which are remarkable in the diversity of different …
molecules, enzyme substrates or cofactors, which are remarkable in the diversity of different …
[HTML][HTML] Fluorine-19 as a covalent active site-directed magnetic resonance probe in aspartate transaminase.
M Martinez-Carrion, JC Slebe, B Boettcher… - Journal of Biological …, 1976 - Elsevier
Phosphypyridoxyl trifluoroethylamine has been synthesized as an active site-directed 19F
NMR probe for aspartate transaminase. This coenzyme derivative adds stoichiometrically to …
NMR probe for aspartate transaminase. This coenzyme derivative adds stoichiometrically to …