Endophytic fungi: a future prospect for breast cancer therapeutics and drug development

S Varghese, MS Jisha, KC Rajeshkumar, V Gajbhiye… - Heliyon, 2024 - cell.com
Globally, breast cancer is a primary contributor to cancer-related fatalities and illnesses
among women. Consequently, there is a pressing need for safe and effective treatments for …

Bioactive Alkaloids as Secondary Metabolites from Plant Endophytic Aspergillus Genus

J Zhu, L Song, S Shen, W Fu, Y Zhu, L Liu - Molecules, 2023 - mdpi.com
Alkaloids represent a large family of natural products with diverse structures and
bioactivities. These compounds and their derivatives have been widely used in clinics to …

Aspergillus niger CJ6 extract with antimicrobial potential promotes in-vitro cytotoxicity and induced apoptosis against MIA PaCa-2 cell line

MP Bhat, B Chakraborty, SK Nagaraja… - Environmental …, 2023 - Elsevier
Nowadays, the increased number of multidrug-resistant strains among pathogens is a
severe public health concern and cancer is posing a great threat for humans. These …

Extraction and characterization of anti-virus anthraquinones from Nicotiana tabacum-derived Aspergillus oryzae YNCA1220

FX Yang, YY Ma, YP Wu, GK Zhao, YP Li, ZJ Li… - Pesticide Biochemistry …, 2023 - Elsevier
In this study, seven novel anthraquinones (1–7) and four described anthraquinones (8–11)
were purified from Nicotiana tabacum-derived Aspergillus oryzae YNCA1220. It is worth …

Exploring the nematicidal mechanisms and control efficiencies of oxalic acid producing Aspergillus tubingensis WF01 against root-knot nematodes

ZY Yang, YC Dai, YQ Mo, JL Wang, L Ma… - Frontiers in …, 2024 - frontiersin.org
Background and aims Root-knot nematodes (RKN; Meloidogyne spp.) are among the highly
prevalent and significantly detrimental pathogens that cause severe economic and yield …

Identification and Characterization of a Plant Endophytic Fungus Paraphaosphaeria sp. JRF11 and Its Growth-Promoting Effects

J Shan, F Peng, J Yu, Q Li - Journal of Fungi, 2024 - mdpi.com
Endophytic fungi establish mutualistic relationships with host plants and can promote the
growth and development of plants. In this study, the endophytic fungus JRF11 was isolated …

[HTML][HTML] Metabolites of medicine food homology-derived endophytic fungi and their activities

J Zhang, Y Zhu, J Si, L Wu - Current Research in Food Science, 2022 - Elsevier
Medicine food homology (MFH) substances not only provide essential nutrients as food but
also have corresponding factors that can prevent and help treat nutritional imbalances …

Endophytic fungi of Panax sokpayensis produce bioactive ginsenoside Compound K in flask fermentation

S Rai, LS Singh, RU Shaanker, K Jeyaram, T Parija… - Scientific Reports, 2024 - nature.com
Endophytes of Panax have the potential to produce their host plant secondary metabolites,
ginsenosides. Panax sokpayensis, an endemic traditional medicinal plant of the Sikkim …

Treasures in our backyard: unleashing the biotechnological potentials of endophytic fungi from Tanzanian mangroves

H Myovela, J Hussein, D Tibuhwa - Natural Product Research, 2024 - Taylor & Francis
Endophytic fungi are useful in a variety of biological processes and may find value in
pharmaceutical settings. However, there hasn't been much research done on the bioactive …

Promising Cytotoxic butenolides from the Soybean endophytic fungus Aspergillus terreus: a combined molecular docking and in-vitro studies

SS El-Hawary, AS Moawad, HS Bahr… - Journal of Applied …, 2023 - academic.oup.com
Aim This study aimed to use one strain many compounds approach (OSMAC) to investigate
the cytotoxic potential of Aspergillus terreus associated with soybean versus several cancer …