Active matter at the interface between materials science and cell biology
D Needleman, Z Dogic - Nature reviews materials, 2017 - nature.com
The remarkable processes that characterize living organisms, such as motility, self-healing
and reproduction, are fuelled by a continuous injection of energy at the microscale. The field …
and reproduction, are fuelled by a continuous injection of energy at the microscale. The field …
Mechanical response of cytoskeletal networks
The cellular cytoskeleton is a dynamic network of filamentous proteins, consisting of
filamentous actin (F‐actin), microtubules, and intermediate filaments. However, these …
filamentous actin (F‐actin), microtubules, and intermediate filaments. However, these …
Orientational order of motile defects in active nematics
The study of liquid crystals at equilibrium has led to fundamental insights into the nature of
ordered materials, as well as to practical applications such as display technologies. Active …
ordered materials, as well as to practical applications such as display technologies. Active …
Self-organized dynamics and the transition to turbulence of confined active nematics
A Opathalage, MM Norton… - Proceedings of the …, 2019 - National Acad Sciences
We study how confinement transforms the chaotic dynamics of bulk microtubule-based
active nematics into regular spatiotemporal patterns. For weak confinements in disks …
active nematics into regular spatiotemporal patterns. For weak confinements in disks …
Topological phonon modes and their role in dynamic instability of microtubules
Microtubules (MTs) are self-assembled hollow protein tubes playing important functions in
live cells. Their building block is a protein called tubulin, which self-assembles in a …
live cells. Their building block is a protein called tubulin, which self-assembles in a …
Thermal fluctuations of grafted microtubules provide evidence of a length-dependent persistence length
Microtubules are hollow cylindrical structures that constitute one of the three major classes
of cytoskeletal filaments. On the mesoscopic length scale of a cell, their material properties …
of cytoskeletal filaments. On the mesoscopic length scale of a cell, their material properties …
Cilia-like beating of active microtubule bundles
The mechanism that drives the regular beating of individual cilia and flagella, as well as
dense ciliary fields, remains unclear. We describe a minimal model system, composed of …
dense ciliary fields, remains unclear. We describe a minimal model system, composed of …
Nanoindentation studies of full and empty viral capsids and the effects of capsid protein mutations on elasticity and strength
JP Michel, IL Ivanovska, MM Gibbons… - Proceedings of the …, 2006 - National Acad Sciences
The elastic properties of capsids of the cowpea chlorotic mottle virus have been examined at
pH 4.8 by nanoindentation measurements with an atomic force microscope. Studies have …
pH 4.8 by nanoindentation measurements with an atomic force microscope. Studies have …
Elastic response, buckling, and instability of microtubules under radial indentation
We tested the mechanical properties of single microtubules by lateral indentation with the tip
of an atomic force microscope. Indentations up to∼ 3.6 nm, ie, 15% of the microtubule …
of an atomic force microscope. Indentations up to∼ 3.6 nm, ie, 15% of the microtubule …
Tunable dynamics of microtubule-based active isotropic gels
We investigate the dynamics of an active gel of bundled microtubules (MTs) that is driven by
clusters of kinesin molecular motors. Upon the addition of ATP, the coordinated action of …
clusters of kinesin molecular motors. Upon the addition of ATP, the coordinated action of …