INTRODUCTION Brain disorders may exhibit shared symptoms and substantial
epidemiological comorbidity, inciting debate about their etiologic overlap. However, detailed …

How and to what extent does extraversion relate to work relevant variables across the
lifespan? In the most extensive quantitative review to date, we summarize results from 97 …

Evidence supports the observational associations of gut microbiota with a variety of
psychiatric disorders, but the causal nature of such associations remains obscure. Aiming to …

Polygenic indexes (PGIs) are DNA-based predictors. Their value for research in many
scientific disciplines is growing rapidly. As a resource for researchers, we used a consistent …

Personality is influenced by genetic and environmental factors and associated with mental
health. However, the underlying genetic determinants are largely unknown. We identified six …

This authoritative handbook is the reference of choice for researchers and students of
personality. Leading authorities describe the most important theoretical approaches in …

Personality traits are the relatively enduring patterns of thoughts, feelings and behaviors that
reflect the tendency to respond in certain ways under certain circumstances. Twin and family …

Occupational stress and high workload are being increasingly recognized as significant
contributors to the diseases and disorders constituting major components of the global …

The mammalian cerebrum performs high-level sensory perception, motor control and
cognitive functions through highly specialized cortical and subcortical structures. Recent …

Recent genome-wide association studies (GWAS) have shown that temperament is strongly
influenced by more than 700 genes that modulate associative conditioning by molecular …