Focal adhesions lie at the convergence of integrin adhesion, signaling and the actin
cytoskeleton. Cells modify focal adhesions in response to changes in the molecular …

Spermatogenesis is the process by which a single spermatogonium develops into 256
spermatozoa, one of which will fertilize the ovum. Since the 1950s when the stages of the …

Epithelial to mesenchymal transition (EMT) occurs during development and cancer
progression to metastasis and results in enhanced cell motility and invasion. Transforming …

With the current access to the whole genomes of various organisms and the completion of
the first draft of the human genome, there is a strong need for a structure-function …

Spermatogenesis is an intriguing but complicated biological process. However, many
studies since the 1960s have focused either on the hormonal events of the hypothalamus …

N-formyl peptide receptors (FPRs) are critical regulators of host defense in phagocytes and
are also expressed in epithelia. FPR signaling and function have been extensively studied …

Interactions of cells with the extracellular matrix are essential for the control of tissue
remodelling, cell migration, and embryogenesis. At the cell–extracellular matrix contact …

Mudskippers are amphibious fishes that have developed morphological and physiological
adaptations to match their unique lifestyles. Here we perform whole-genome sequencing of …

A cornerstone of many cell-signalling events rests on reversible phosphorylation of tyrosine
residues on proteins. The reversibility relies on the coordinated actions of protein tyrosine …

The ability of the biomimetic peptides YIGSR, PHSRN and RGD to selectively affect
adhesion and migration of human microvascular endothelial cells (MVEC) and vascular …