Biomimetic strategies for targeted nanoparticle delivery

D Dehaini, RH Fang, L Zhang - Bioengineering & translational …, 2016 - Wiley Online Library
Nanoparticle‐based drug delivery and imaging platforms have become increasingly popular
over the past several decades. Among different design parameters that can affect their …

Bioengineered Escherichia coli Nissle 1917 for tumour‐targeting therapy

X Yu, C Lin, J Yu, Q Qi, Q Wang - Microbial biotechnology, 2020 - Wiley Online Library
Bacterial vectors, as microscopic living 'robotic factories', can be reprogrammed into
microscopic living 'robotic factories', using a top‐down bioengineering approach to produce …

Bacterial ghosts-based vaccine and drug delivery systems

H Chen, H Ji, X Kong, P Lei, Q Yang, W Wu, L Jin… - Pharmaceutics, 2021 - mdpi.com
Bacterial ghosts (BGs) are empty bacterial envelopes of Gram-negative bacteria produced
by controlled expressions of cloned gene E, forming a lysis tunnel structure within the …

Advances of bacteria-based delivery systems for modulating tumor microenvironment

S Li, H Yue, S Wang, X Li, X Wang, P Guo, G Ma… - Advanced drug delivery …, 2022 - Elsevier
The components and hospitable properties of tumor microenvironment (TME) are associated
with tumor progression. Recently, TME modulating vectors and strategies have garnished …

Bacterial components as naturally inspired nano-carriers for drug/gene delivery and immunization: Set the bugs to work?

F Farjadian, M Moghoofei, S Mirkiani, A Ghasemi… - Biotechnology …, 2018 - Elsevier
Drug delivery is a rapidly growing area of research motivated by the nanotechnology
revolution, the ideal of personalized medicine, and the desire to reduce the side effects of …

Vaccination against bacterial infections: challenges, progress, and new approaches with a focus on intracellular bacteria

A Osterloh - Vaccines, 2022 - mdpi.com
Many bacterial infections are major health problems worldwide, and treatment of many of
these infectious diseases is becoming increasingly difficult due to the development of …

Prospective and challenges of live bacterial therapeutics from a superhero Escherichia coli Nissle 1917

SSW Effendi, IS Ng - Critical Reviews in Microbiology, 2023 - Taylor & Francis
Abstract Escherichia coli Nissle 1917 (EcN), the active component of Mutaflor (R), is a
notable probiotic from Gram-negative to treat Crohn's disease and irritable bowel syndrome …

The development of ghost vaccines trials

AM Batah, TA Ahmad - Expert review of vaccines, 2020 - Taylor & Francis
Introduction Bacterial ghosts are intact bacterial cell envelopes that are emptied of their
content by gentle biological or chemical poring methods. Ghost techniques increase the …

Recent update on bacteria as a delivery carrier in cancer therapy: from evil to allies

M Pandey, H Choudhury, PAP Vijayagomaran… - Pharmaceutical …, 2022 - Springer
Cancer is associated with a comprehensive burden that significantly affects patient's quality
of life. Even though patients' disease condition is improving following conventional …

Biomimetic and bioinspired strategies for oral drug delivery

X Hu, G Yang, S Chen, S Luo, J Zhang - Biomaterials science, 2020 - pubs.rsc.org
Oral drug delivery remains the most preferred approach due to its multiple advantages.
Recently there has been increasing interest in the development of advanced vehicles for …