A framework to advance biomarker development in the diagnosis, outcome prediction, and treatment of traumatic brain injury

EA Wilde, IB Wanner, K Kenney, J Gill… - Journal of …, 2022 - liebertpub.com
Multi-modal biomarkers (eg, imaging, blood-based, physiological) of unique traumatic brain
injury (TBI) endophenotypes are necessary to guide the development of personalized and …

[HTML][HTML] MRI factors associated with cognitive functioning after acute onset brain injury: systematic review and meta-analysis

MMLH Verhulst, AB Glimmerveen, CM van Heugten… - NeuroImage: Clinical, 2023 - Elsevier
Impairments of memory, attention, and executive functioning are frequently reported after
acute onset brain injury. MRI markers hold potential to contribute to identification of patients …

Association of intensive vs standard blood pressure control with cerebral blood flow: secondary analysis of the SPRINT MIND randomized clinical trial

S Dolui, JA Detre, SA Gaussoin, JS Herrick… - JAMA …, 2022 - jamanetwork.com
Importance Antihypertensive treatments benefit cerebrovascular health and cognitive
function in patients with hypertension, but it is uncertain whether an intensive blood pressure …

[HTML][HTML] Temporal dynamics of cerebral blood flow during the first year after moderate-severe traumatic brain injury: A longitudinal perfusion MRI study

NL Gaggi, JB Ware, S Dolui, D Brennan, J Torrellas… - NeuroImage: Clinical, 2023 - Elsevier
Traumatic brain injury (TBI) is associated with alterations in cerebral blood flow (CBF), which
may underlie functional disability and precipitate TBI-induced neurodegeneration. Although …

Anacardic acid improves neurological deficits in traumatic brain injury by anti-ferroptosis and anti-inflammation

Y Liu, Z Zhao, J Guo, Y Ma, J Li, H Ji, Z Chen… - Experimental …, 2023 - Elsevier
Background Traumatic brain injury (TBI) is an important cause of disability and death. TBI
leads to multiple forms of nerve cell death including ferroptosis due to iron-dependent lipid …

Longitudinal dynamics of microvascular recovery after acquired cortical injury

X Lin, L Chen, A Jullienne, H Zhang, A Salehi… - Acta neuropathologica …, 2022 - Springer
Acquired brain injuries due to trauma damage the cortical vasculature, which in turn impairs
blood flow to injured tissues. There are reports of vascular morphological recovery following …

[HTML][HTML] Assessment of vibration modulated regional cerebral blood flow with MRI

L Kong, S Qiu, Y Chen, Z He, P Huang, Q He… - NeuroImage, 2023 - Elsevier
Human brain experiences vibration of certain magnitude and frequency during various
physical activities such as vehicle transportation and machine operation, which may cause …

Arterial spin labeling reveals elevated cerebral blood flow with distinct clusters of hypo-and hyperperfusion after traumatic brain injury

L Xu, JB Ware, JJ Kim, P Shahim… - Journal of …, 2021 - liebertpub.com
Imaging detection of brain perfusion alterations after traumatic brain injury (TBI) may provide
prognostic insights. In this study, we used arterial spin labeling (ASL) to quantify cross …

A population-based study of pre-existing health conditions in traumatic brain injury

KC Dell, EC Grossner, J Staph, P Schatz… - Neurotrauma …, 2021 - liebertpub.com
Health factors impacting both the occurrence of, and recovery from traumatic brain injury
(TBI) vary in complexity, and present genuine challenges to researchers and healthcare …

Transcranial photobiomodulation and chronic traumatic brain injury

NL Gaggi, NL Roy, X Song, AL Peterson, DV Iosifescu… - Photonics, 2024 - mdpi.com
Traumatic brain injury (TBI) is a common cause of neurologic morbidity for which few
effective therapies exist, especially during the chronic stage. A potential therapy for chronic …