Cerebral plasticity: Windows of opportunity in the developing brain

FY Ismail, A Fatemi, MV Johnston - European journal of paediatric …, 2017 - Elsevier
Background Neuroplasticity refers to the inherently dynamic biological capacity of the central
nervous system (CNS) to undergo maturation, change structurally and functionally in …

Serotonin and neuroplasticity–links between molecular, functional and structural pathophysiology in depression

C Kraus, E Castrén, S Kasper… - … & Biobehavioral Reviews, 2017 - Elsevier
Serotonin modulates neuroplasticity, especially during early life, and dysfunctions in both
systems likewise contribute to pathophysiology of depression. Recent findings demonstrate …

Critical Period After Stroke Study (CPASS): A phase II clinical trial testing an optimal time for motor recovery after stroke in humans

AW Dromerick, S Geed, J Barth… - Proceedings of the …, 2021 - National Acad Sciences
Restoration of human brain function after injury is a signal challenge for translational
neuroscience. Rodent stroke recovery studies identify an optimal or sensitive period for …

The role of BDNF on neural plasticity in depression

T Yang, Z Nie, H Shu, Y Kuang, X Chen… - Frontiers in cellular …, 2020 - frontiersin.org
Using behavioral, pharmacological, and molecular methods, lots of studies reveal that
depression is closely related to the abnormal neural plasticity processes occurring in the …

Critical periods in speech perception: new directions

JF Werker, TK Hensch - Annual review of psychology, 2015 - annualreviews.org
A continuing debate in language acquisition research is whether there are critical periods
(CPs) in development during which the system is most responsive to environmental input …

Brain-derived neurotrophic factor in mood disorders and antidepressant treatments

E Castrén, M Kojima - Neurobiology of disease, 2017 - Elsevier
Levels of brain-derived neurotrophic factor (BDNF) are reduced in the brain and serum of
depressed patients and at least the reduction in serum levels is reversible upon successful …

Critical period regulation across multiple timescales

RK Reh, BG Dias, CA Nelson III… - Proceedings of the …, 2020 - National Acad Sciences
Brain plasticity is dynamically regulated across the life span, peaking during windows of
early life. Typically assessed in the physiological range of milliseconds (real time), these …

Balancing plasticity/stability across brain development

AE Takesian, TK Hensch - Progress in brain research, 2013 - Elsevier
The potency of the environment to shape brain function changes dramatically across the
lifespan. Neural circuits exhibit profound plasticity during early life and are later stabilized. A …

Neuronal plasticity and neurotrophic factors in drug responses

E Castrén, H Antila - Molecular psychiatry, 2017 - nature.com
Neurotrophic factors, particularly brain-derived neurotrophic factor (BDNF) and other
members of the neurotrophin family, are central mediators of the activity-dependent plasticity …

Environment and brain plasticity: towards an endogenous pharmacotherapy

A Sale, N Berardi, L Maffei - Physiological reviews, 2014 - journals.physiology.org
Brain plasticity refers to the remarkable property of cerebral neurons to change their
structure and function in response to experience, a fundamental theoretical theme in the …