Piano stool Ru (II)-arene complexes having three monodentate legs: A comprehensive review on their development as anticancer therapeutics over the past decade

S Swaminathan, J Haribabu, N Balakrishnan… - Coordination chemistry …, 2022 - Elsevier
The popularity of RAPTA-C in in vivo studies has steered the way for complexes of the type
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …

Target based chemotherapeutic advancement of ruthenium complexes

BK Kundu, S Mukhopadhyay - Coordination Chemistry Reviews, 2021 - Elsevier
Over the last few years, great emphasis has been given to develop ruthenium complexes to
act as target specified chemotherapeutic agents. Indeed, there are few reviews available …

Impact of aliphatic acyl and aromatic thioamide substituents on the anticancer activity of Ru (ii)-p-cymene complexes with acylthiourea ligands—in vitro and in vivo …

S Swaminathan, J Haribabu, MKM Subarkhan… - Dalton …, 2021 - pubs.rsc.org
Six different acylthiourea ligands (L1–L6) and their corresponding Ru (II)-p-cymene
complexes (P1–P6) were designed to explore the structure–activity relationship of the …

Coordination behavior of acylthiourea ligands in their Ru (II)–benzene complexes─ structures and anticancer activity

S Swaminathan, J Haribabu… - …, 2022 - ACS Publications
Acylthiourea ligands have applications in both synthetic and applied chemistry. The skeleton
of the ligand contains several heteroatoms which offer variable coordination modes in their …

An overview on the anticancer activity of Ru (II)/acylthiourea complexes

GH Ribeiro, AR Costa, AR de Souza… - Coordination Chemistry …, 2023 - Elsevier
This review outlines research on the development of ruthenium complexes containing
acylthiourea ligands with potential antitumor activity, which have been leveraged in recent …

Hinged Bipodal Furoylthiourea-Based Ru(II)-Arene Complexes: Effect of (ortho, meta, or para)-Substitution on Coordination and Anticancer Activity

S Swaminathan, J Haribabu, M Dharmasivam… - Inorganic …, 2023 - ACS Publications
We set out to design and synthesize bipodal ligands with the phenyl group as the spacer
and varied the substitution on the spacer between ortho (L1), meta (L2), and para (L3). The …

[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies

S Adhikari, P Nath, A Das, A Datta, N Baildya… - Biomedicine & …, 2024 - Elsevier
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …

Multi-Biofunctional Properties of Phytofabricated Selenium Nanoparticles From Carica papaya Fruit Extract: Antioxidant, Antimicrobial, Antimycotoxin, Anticancer, and …

SR Vundela, NK Kalagatur, A Nagaraj… - Frontiers in …, 2022 - frontiersin.org
The present study focused on phytofabrication of selenium nanoparticles (SeNPs) from
Carica papaya extract and exploration of their multi-biofunctional features. Total phenolics …

Effect of N-benzyl group in indole scaffold of thiosemicarbazones on the biological activity of their Pd (II) complexes: DFT, biomolecular interactions, in silico docking …

N Balakrishnan, J Haribabu, RE Malekshah… - Inorganica Chimica …, 2022 - Elsevier
A series of N-benzyl substituted indole-based thiosemicarbazone (TSC) ligands (L4-L6) and
palladium (II) TSC complexes,[Pd (L) 2](1–6)(L= monoanionic bidentate un/N-substituted …

Influence of Indole-N Substitution of Thiosemicarbazones in Cationic Ru(II)(η6-Benzene) Complexes on Their Anticancer Activity

N Balakrishnan, J Haribabu, M Dharmasivam… - …, 2023 - ACS Publications
Indole thiosemicarbazones (TSCs) and their complexes are known to possess various
biological activities. The variation in anticancer activity with different indole-N substituents of …