Tumor immunity and immunotherapy for HPV-related cancers

AA Shamseddine, B Burman, NY Lee, D Zamarin… - Cancer discovery, 2021 - AACR
Human papillomavirus (HPV) infection drives tumorigenesis in the majority of cervical,
oropharyngeal, anal, and vulvar cancers. Genetic and epidemiologic evidence has …

Intratumoural microbiota: a new frontier in cancer development and therapy

Y Cao, H Xia, X Tan, C Shi, Y Ma, D Meng… - … and Targeted Therapy, 2024 - nature.com
Human microorganisms, including bacteria, fungi, and viruses, play key roles in several
physiological and pathological processes. Some studies discovered that tumour tissues …

Effect of human papillomavirus infection on the immune system and its role in the course of cervical cancer

D Song, H Li, H Li, J Dai - Oncology letters, 2015 - spandidos-publications.com
Human papillomavirus (HPV) is widely known as a cause of cervical intraepithelial
neoplasia (CIN) and cervical cancer. The mechanisms involved have been studied by …

[HTML][HTML] Interaction of human papillomaviruses with the host immune system: a well evolved relationship

IH Frazer - Virology, 2009 - Elsevier
Human papillomavirus (HPV) infections are generally long lasting, and a host immune
response to infection is hard to detect. Nevertheless immunocompromised subjects control …

Infiltrating T-cell markers in cervical carcinogenesis: a systematic review and meta-analysis

TR Litwin, SR Irvin, RL Chornock… - British journal of …, 2021 - nature.com
Background The host adaptive immune response helps determine which cervical HPV
infections persist and progress to precancer and cancer, and systematic characterisation of …

HPVTIMER: A shiny web application for tumor immune estimation in human papillomavirus‐associated cancers

L Liu, Y Xie, H Yang, A Lin, M Dong, H Wang, C Zhang… - Imeta, 2023 - Wiley Online Library
The tumor immune microenvironment (TIME) is closely associated with tumor formation,
particularly linked to the human papillomavirus (HPV), and regulates tumor initiation …

Immune responses to human papilloma viruses

MA Stanley - Indian Journal of Medical Research, 2009 - journals.lww.com
HPV infection in the genital tract is common in young sexually active individuals, the majority
of whom clear the infection without overt clinical disease. However most of those who …

The immune microenvironment in human papilloma virus-induced cervical lesions—Evidence for estrogen as an immunomodulator

J Rs - Frontiers in Cellular and Infection Microbiology, 2021 - frontiersin.org
Globally, human papilloma virus (HPV) infection is a common sexually transmitted disease.
However, most of the HPV infections eventually resolve aided by the body's efficient cell …

The prognostic value of immune factors in the tumor microenvironment of penile squamous cell carcinoma

SR Ottenhof, RS Djajadiningrat, HH Thygesen… - Frontiers in …, 2018 - frontiersin.org
The host's immune system plays a pivotal role in many tumor types, including squamous cell
carcinomas (SCCs). We aim to identify immunological prognosticators for lymph node …

[HTML][HTML] Suppl 2: the invisible enemy–how human papillomaviruses avoid recognition and clearance by the host immune system

AK Grabowska, AB Riemer - The open virology journal, 2012 - ncbi.nlm.nih.gov
Human papillomavirus (HPV) needs to persist in squamous epithelia for a certain amount of
time to complete its reproductive cycle. Therefore, the virus has evolved multiple immune …