On the distance to the transition state of protein folding in optical tweezers experiments

CG Corrêa, CAM Wilson - Biophysical Reviews, 2025 - Springer
The distance to the transition state (x‡) is an important parameter for understanding the
energy landscape of chemical reactions. In protein folding, x‡ represents the distance to the …

Cracking Controls ATP Hydrolysis in the catalytic domain of a P-ATPase

MA Placenti, SA Gache, RM Gonzalez-Lebrero… - bioRxiv, 2025 - biorxiv.org
Membrane transporters are essential for cell homeostasis. Among them P-type ATPases,
which couple ATP hydrolysis to solute transport, play a key role. Despite extensive research …