[HTML][HTML] The power of human stem cell-based systems in the study of neurodevelopmental disorders
M Jhanji, EM York, SB Lizarraga - Current Opinion in Neurobiology, 2024 - Elsevier
Highlights•Overview of convergent disease mechanisms across NDDs identified in 2D & 3D
models.•Discuss therapeutic implications for various ASOs and gene editing …
models.•Discuss therapeutic implications for various ASOs and gene editing …
The pleiotropic spectrum of proximal 16p11. 2 CNVs
Recurrent genomic rearrangements at 16p11. 2 BP4-5 represent one of the most common
causes of genomic disorders. Originally associated with increased risk for autism spectrum …
causes of genomic disorders. Originally associated with increased risk for autism spectrum …
Dysregulation of the mTOR-FMRP pathway and synaptic plasticity in an environmental model of ASD
Abstract Autism Spectrum Disorder (ASD) is caused by genetic, epigenetic, and
environmental factors. Mutations in the human FMR1 gene, encoding the Fragile X …
environmental factors. Mutations in the human FMR1 gene, encoding the Fragile X …
Reply to: “Correspondence to bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca2+ entry and accelerated differentiation …
We appreciate the opportunity to respond to Yde Ohki and colleagues' commentary [1] on
our recent publication [2]. We agree with the authors that sufficient and accurate information …
our recent publication [2]. We agree with the authors that sufficient and accurate information …