The serum-and glucocorticoid-inducible kinase-1 (SGK1) is ubiquitously expressed and
under genomic control by cell stress (including cell shrinkage) and hormones (including …

Type 2 diabetes mellitus is a complex metabolic disease that is caused by insulin resistance
and β-cell dysfunction. Furthermore, type 2 diabetes has an evident genetic component and …

Triple negative breast cancer (TNBC) is a deadly form of breast cancer due to the
development of resistance to chemotherapy affecting over 30% of patients. New …

Abstract Development and routine tissue homeostasis require a high turnover of apoptotic
cells. These cells are removed by professional and non-professional phagocytes via …

Insulin, downstream of Akt activation, promotes glucose uptake into fat and muscle cells to
lower postprandial blood glucose, an enforced change in cellular metabolism to maintain …

The success of adoptively transferred tumor-directed T cells requires them to survive and
expand in vivo. Most tumors, however, employ immune evasion mechanisms, including the …

The efficacy of antitumor immunity is associated with the metabolic state of cytotoxic T cells,
which is sensitive to the tumor microenvironment. Whether ionic signals affect adaptive …

The outlined recent findings advanced our understanding of the molecular regulation of
SGK1 as well as the role of the kinase in renal physiology and the pathophysiology of renal …

The present brief review highlights the putative role of the serum‐and glucocorticoid‐
inducible‐kinase‐1 (SGK1) in the regulation of neuronal function. SGK1 is genomically …

The epithelial sodium channel (ENaC) plays an important role in transepithelial Na+
absorption; hence its function is essential for maintaining Na+ and fluid homeostasis and …