Nitric oxide and superoxide, which are produced by several cell types, rapidly combine to
form peroxynitrite. This reaction can result in nitric oxide scavenging, and thus mitigation of …

Nitrogen oxides (NOx), regarded in the past primarily as toxic air pollutants, have recently
been shown to be bioactive species formed endogenously in the human lung. The …

Endothelial cells, macrophages, neutrophils, and neuronal cells generate superoxide (O 2−)
and nitric oxide (· NO) which can combine to form peroxynitrite anion (ONOO−) …

Peroxynitrite formation by rat alveolar macrophages activated with phorbol 12-myristate 13-
acetate was assayed by the Cu, Zn superoxide dismutase-catalyzed nitration of 4 …

, Introduction p. Nitric (Oxide Synthase lsoforms: Characterization and Tissue and
Subcellular Distribution p, Purification and Properties A Constitutive Nitric Oxide SynthaSe p …

The findings reviewed above leave no doubt as to the complexity of actions of TGF-beta, IL-
4, and IL-10 on monocytes/macrophages. Along with MDF, whose actions were recently …

Vascular endothelial cells, smooth muscle cells, macrophages, neutrophils, Kupffer cells
and other diverse cell types generate superoxide (O2.-) and nitric oxide (. NO), which can …

Tumor necrosis factor‐α (TNF‐α) is a polypeptide hormone newly synthesized by different
cell types upon stimulation with endotoxin, inflammatory mediators (C5a anaphylatoxin), or …

Macrophages can metabolize arginine to nitric oxide in quantities that inhibit pathogens or
nearby host cells. They can instead metabolize arginine to ornithine (a precursor of …

Macrophages can recognize and eliminate tumor cells. To this effect, these cells use a
variety of cytotoxic effectors. Recent work has paid particular attention to nitric oxide (NO) …