Studies on survivin over the past 2–3 years have shown that survivin possesses multiple
subcellular localizations and is a multi‐functional molecule involved in many aspects of …

The dysregulation of the splicing process has emerged as a novel hallmark of metabolic and
tumor pathologies. In breast cancer (BCa), which represents the most diagnosed cancer …

Purpose: Survivin is an inhibitor of apoptosis protein (IAP) that is highly expressed in many
cancers and represents an attractive molecule for targeted cancer therapy. Although …

Survivin plays a crucial role in cell division particularly during the development of the fetus,
in the onset and progression of most tumors and is found expressed in a few terminally …

The purpose of this study was the overview of current knowledge regarding the use of
survivin and its isoforms in prognosis and treatment of breast cancer. An advanced search of …

The survivin protein, a member of the inhibitors of apoptosis (IAP) family, has gained
popularity as a therapeutic target for cancer due to its selective expression in tumor cells and …

Since the acquired resistance of cells to apoptosis is one of the major hallmarks of cancer,
the endogenous inhibitors of apoptosis can be regarded as promising targets in the design …

Survivin is an attractive target in cancer therapy. Previous studies have demonstrated that
survivin dominant-negative mutants T34A and C84A were able to induce apoptosis in …

Background We previously reported an HLA-A24-restricted cytotoxic T-cell epitope, Survivin-
2B80-88, derived from a splice variant of survivin, survivin-2B. In this report, we show a …

The aim of the present study was to detect the expression of survivin in human lung cancer
and to investigate the influence of its downregulation on the biological behavior of A549 …