Structural characterization of Cu2+, Ni2+ and Zn2+ binding sites of model peptides associated with neurodegenerative diseases
C Migliorini, E Porciatti, M Luczkowski… - Coordination Chemistry …, 2012 - Elsevier
Metal ions, especially redox active copper, are thought to play critical roles in
neurodegenerative disorders. As a matter of fact, metal binding may result into severe …
neurodegenerative disorders. As a matter of fact, metal binding may result into severe …
Interactions of Cu2+ with prion family peptide fragments: Considerations on affinity, speciation and coordination
The review describes the stability and the coordination modes of Cu2+ complexes with
different regions of N-terminus prion proteins. The structural features of the different metal …
different regions of N-terminus prion proteins. The structural features of the different metal …
Preparation and characterization of iron-chelating peptides from whey protein: An alternative approach for chemical iron fortification
Iron fortification of staple food is a strategy utilized worldwide to address the concern of
dietary iron deficiency. However, traditional salt-based fortification methods have limitations …
dietary iron deficiency. However, traditional salt-based fortification methods have limitations …
Biophysical and in vitro absorption studies of iron chelating peptide from barley proteins
Isothermal titration calorimetry (ITC) and tandem mass spectrometry (MS/MS) were used to
study the interaction between Fe 2+ and the heptapeptide (SVNVPLY) from barley protein …
study the interaction between Fe 2+ and the heptapeptide (SVNVPLY) from barley protein …
High affinity binding between copper and full-length prion protein identified by two different techniques
AR Thompsett, SR Abdelraheim, M Daniels… - Journal of Biological …, 2005 - ASBMB
The cellular prion protein is known to be a copper-binding protein. Despite the wide range of
studies on the copper binding of PrP, there have been no studies to determine the affinity of …
studies on the copper binding of PrP, there have been no studies to determine the affinity of …
The Inorganic Perspective of Nerve Growth Factor: Interactions of Cu2+ and Zn2+ with the N‐Terminus Fragment of Nerve Growth Factor Encompassing the …
There is a significant overlap between brain areas with Zn2+ and Cu2+ pathological dys‐
homeostasis and those in which the nerve growth factor (NGF) performs its biological role …
homeostasis and those in which the nerve growth factor (NGF) performs its biological role …
Transition metal complexes of terminally protected peptides containing histidyl residues
Histidine-containing peptide fragments of prion protein are efficient ligands to bind various
transition metal ions and they have high selectivity in metal binding. The metal ion affinity …
transition metal ions and they have high selectivity in metal binding. The metal ion affinity …
Copper, BDNF and Its N‐terminal Domain: Inorganic Features and Biological Perspectives
Brain‐derived neurotrophic factor (BDNF) is a neurotrophin that influences development,
maintenance, survival, and synaptic plasticity of central and peripheral nervous systems …
maintenance, survival, and synaptic plasticity of central and peripheral nervous systems …
Flexible structures and ligand interactions of tandem repeats consisting of proline, glycine, asparagine, serine, and/or threonine rich oligopeptides in proteins
N Matsushima, H Yoshida, Y Kumaki… - Current Protein and …, 2008 - ingentaconnect.com
Tandem repeats occur in 14&percnt of all proteins. The repeat unit lengths range from a
single amino acid to more than 100 residues and the repeat number is sometimes over 100 …
single amino acid to more than 100 residues and the repeat number is sometimes over 100 …
Copper (II) binding properties of an octapeptide fragment from the R3 region of tau protein: A combined potentiometric, spectroscopic and mass spectrometric study
BD Balogh, B Szakács, G Di Natale, G Tabbì… - Journal of Inorganic …, 2021 - Elsevier
The copper (II) complexes of a peptide fragment of the R3 domain of tau protein (tau (326–
333) Ac-GNIHHKPG-NH 2) and its mutants (Ac-GNGHHKPG-NH 2, Ac-GNIHHKAG-NH 2, Ac …
333) Ac-GNIHHKPG-NH 2) and its mutants (Ac-GNGHHKPG-NH 2, Ac-GNIHHKAG-NH 2, Ac …