Metabolomics: towards understanding traditional Chinese medicine

A Zhang, H Sun, Z Wang, W Sun, P Wang… - Planta …, 2010 - thieme-connect.com
Metabolomics represent a global understanding of metabolite complement of integrated
living systems and dynamic responses to the changes of both endogenous and exogenous …

The developmental, molecular, and transport biology of Malpighian tubules

KW Beyenbach, H Skaer… - Annual review of …, 2010 - annualreviews.org
Molecular biology is reaching new depths in our understanding of the development and
physiology of Malpighian tubules. In Diptera, Malpighian tubules derive from ectodermal …

Optimizing the use of quality control samples for signal drift correction in large-scale urine metabolic profiling studies

MA Kamleh, TMD Ebbels, K Spagou… - Analytical …, 2012 - ACS Publications
The evident importance of metabolic profiling for biomarker discovery and hypothesis
generation has led to interest in incorporating this technique into large-scale studies, eg …

Advances in methods for the determination of biologically relevant lipid peroxidation products

CM Spickett, I Wiswedel, W Siems, K Zarkovic… - Free radical …, 2010 - Taylor & Francis
Lipid peroxidation is recognized to be an important contributor to many chronic diseases,
especially those of an inflammatory pathology. In addition to their value as markers of …

1H NMR and UHPLC/Q-Orbitrap-MS-Based Metabolomics Combined with 16S rRNA Gut Microbiota Analysis Revealed the Potential Regulation Mechanism of …

LM Wang, P Wang, T Teka, YC Zhang… - Journal of Agricultural …, 2020 - ACS Publications
Hyperuricemia seriously jeopardizes human health by increasing the risk of several
diseases, such as gout and stroke. Nuciferine is able to alleviate hyperuricemia significantly …

Network analysis: tackling complex data to study plant metabolism

D Toubiana, AR Fernie, Z Nikoloski, A Fait - Trends in biotechnology, 2013 - cell.com
Incomplete knowledge of biochemical pathways makes the holistic description of plant
metabolism a non-trivial undertaking. Sensitive analytical platforms, which are capable of …

Proteomics of gliomas: initial biomarker discovery and evolution of technology

J Kalinina, J Peng, JC Ritchie, EG Van Meir - Neuro-oncology, 2011 - academic.oup.com
Gliomas are a group of aggressive brain tumors that diffusely infiltrate adjacent brain tissues,
rendering them largely incurable, even with multiple treatment modalities and agents. Mostly …

Metabolomics to unveil and understand phenotypic diversity between pathogen populations

R t'Kindt, RA Scheltema, A Jankevics… - PLoS neglected …, 2010 - journals.plos.org
Leishmaniasis is a debilitating disease caused by the parasite Leishmania. There is
extensive clinical polymorphism, including variable responsiveness to treatment. We study …

Metabolomic Characterization of the Salt Stress Response in Streptomyces coelicolor

S Kol, ME Merlo, RA Scheltema… - Applied and …, 2010 - Am Soc Microbiol
The humicolous actinomycete Streptomyces coelicolor routinely adapts to a wide variety of
habitats and rapidly changing environments. Upon salt stress, the organism is also known to …

Mapping an Atlas of Tissue-Specific Drosophila melanogaster Metabolomes by High Resolution Mass Spectrometry

VR Chintapalli, M Al Bratty, D Korzekwa, DG Watson… - PloS one, 2013 - journals.plos.org
Metabolomics can provide exciting insights into organismal function, but most work on
simple models has focussed on the whole organism metabolome, so missing the …