Recent advances in clinical practice: management of inflammatory bowel disease during the COVID-19 pandemic

S Lin, LHS Lau, N Chanchlani, NA Kennedy, SC Ng - Gut, 2022 - gut.bmj.com
The COVID-19 pandemic has raised considerable concerns that patients with inflammatory
bowel disease (IBD), particularly those treated with immunosuppressive therapies, may …

Expert consensus: main risk factors for poor prognosis in COVID-19 and the implications for targeted measures against SARS-CoV-2

FJ Candel, P Barreiro, M Salavert, A Cabello… - Viruses, 2023 - mdpi.com
The clinical evolution of patients infected with the Severe Acute Respiratory Coronavirus
type 2 (SARS-CoV-2) depends on the complex interplay between viral and host factors. The …

Changes in COVID-19-related mortality across key demographic and clinical subgroups in England from 2020 to 2022: a retrospective cohort study using the …

L Nab, EPK Parker, CD Andrews, WJ Hulme… - The Lancet public …, 2023 - thelancet.com
Background COVID-19 has been shown to differently affect various demographic and
clinical population subgroups. We aimed to describe trends in absolute and relative COVID …

Humoral and cellular immunogenicity to a second dose of COVID-19 vaccine BNT162b2 in people receiving methotrexate or targeted immunosuppression: a …

SK Mahil, K Bechman, A Raharja… - The Lancet …, 2022 - thelancet.com
Background COVID-19 vaccines have robust immunogenicity in the general population.
However, data for individuals with immune-mediated inflammatory diseases who are taking …

Remdesivir reduced mortality in immunocompromised patients hospitalized for COVID-19 across variant waves: findings from routine clinical practice

E Mozaffari, A Chandak, RL Gottlieb… - Clinical Infectious …, 2023 - academic.oup.com
Background Immunocompromised patients are at high risk of severe coronavirus disease
2019 (COVID-19) and death, yet treatment strategies for immunocompromised patients …

COVID-19 vaccine effectiveness against omicron (B. 1.1. 529) variant infection and hospitalisation in patients taking immunosuppressive medications: a retrospective …

M Risk, SS Hayek, E Schiopu, L Yuan… - The Lancet …, 2022 - thelancet.com
Background There is a scarcity of research regarding the effectiveness of the mRNA-1273
(Moderna) and BNT162b2 (Pfizer-BioNTech) COVID-19 vaccines in patients taking …

[HTML][HTML] Risk of COVID-19 breakthrough infection and hospitalization in individuals with comorbidities

PD Smits, S Gratzl, M Simonov, SK Nachimuthu… - Vaccine, 2023 - Elsevier
Background The successful development of multiple COVID-19 vaccines has led to a global
vaccination effort to reduce severe COVID-19 infection and mortality. However, the …

COVID-19 infection and hospitalization risk according to vaccination status and DMARD treatment in patients with rheumatoid arthritis

R Cordtz, S Kristensen, R Westermann, K Duch… - …, 2023 - academic.oup.com
Objectives The objectives of this study were to investigate the incidence of COVID-19
hospitalization in unvaccinated and vaccinated patients with RA compared with matched …

Ethnic disparities in COVID-19 outcomes: a multinational cohort study of 20 million individuals from England and Canada

F Zaccardi, PS Tan, BR Shah, K Everett, AK Clift… - BMC Public Health, 2023 - Springer
Background Heterogeneous studies have demonstrated ethnic inequalities in the risk of
SARS-CoV-2 infection and adverse COVID-19 outcomes. This study evaluates the …

[HTML][HTML] Disparities in COVID-19 mortality amongst the immunosuppressed: A systematic review and meta-analysis for enhanced disease surveillance

M Leston, W Elson, JM Ordóñez-Mena, D Kar… - Journal of Infection, 2024 - Elsevier
Background Effective disease surveillance, including that for COVID-19, is compromised
without a standardised method for categorising the immunosuppressed as a clinical risk …