I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Contributing Authors Isam Alobid, MD, PhD1, Nithin D. Adappa, MD2, Henry P. Barham,
MD3, Thiago Bezerra, MD4, Nadieska Caballero, MD5, Eugene G. Chang, MD6, Gaurav …

Background To date, no study has evaluated the diversity of TH cell cytokine patterns of
patients with chronic rhinosinusitis (CRS) among centers in different continents using …

The methodology for EPOS2012 has been the same as for the other two productions.
Leaders in the field were invited to critically appraise the literature and write a report on a …

Chronic rhinosinusitis (CRS) is a complex disease consisting of several disease variants
with different underlying pathophysiologies. Limited knowledge of the mechanisms of these …

Chronic rhinosinusitis (CRS) is a broad clinical syndrome that is characterized by prolonged
mucosal inflammation of the nose and paranasal sinuses, and is typically divided into two …

Chronic rhinosinusitis with nasal polyps (CRS w NP) is a complex inflammatory condition
that affects a large proportion of the population world‐wide and is associated with high cost …

Chronic rhinosinusitis (CRS) is a public health problem that has a significant socio-
economic impact. Moreover, the complexity of this disease due to its heterogeneous nature …

Background Bacteria and fungi are believed to influence mucosal inflammation in chronic
rhinosinusitis (CRS). However their presence and relationship to disease is debated. This …

Rhinosinusitis is one of the most commonly diagnosed diseases in the United States.
Analysis of the Centers for Disease Control and Preventionesponsored 2010 US National …