[HTML][HTML] Characteristics of SARS-CoV-2 and COVID-19

B Hu, H Guo, P Zhou, ZL Shi - Nature reviews microbiology, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute …

Monocytes and Macrophages in COVID-19

R Knoll, JL Schultze, J Schulte-Schrepping - Frontiers in immunology, 2021 - frontiersin.org
COVID-19 is a contagious viral disease caused by SARS-CoV-2 that led to an ongoing
pandemic with massive global health and socioeconomic consequences. The disease is …

SARS-CoV-2 infection and persistence in the human body and brain at autopsy

SR Stein, SC Ramelli, A Grazioli, JY Chung, M Singh… - Nature, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction,–
during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia

RA Grant, L Morales-Nebreda, NS Markov… - Nature, 2021 - nature.com
Some patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
develop severe pneumonia and acute respiratory distress syndrome (ARDS). Distinct …

Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA. 1 attenuation

DY Chen, CV Chin, D Kenney, AH Tavares, N Khan… - Nature, 2023 - nature.com
Abstract The SARS-CoV-2 Omicron variant is more immune evasive and less virulent than
other major viral variants that have so far been recognized,,,,,,,,,,–. The Omicron spike (S) …

SARS-CoV-2 vaccination induces mucosal antibody responses in previously infected individuals

K Sano, D Bhavsar, G Singh, D Floda… - Nature …, 2022 - nature.com
Immune responses at the respiratory mucosal interface are critical to prevent respiratory
infections but it is unclear to what extent antigen specific mucosal secretory IgA (SIgA) …

COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City

AC Borczuk, SP Salvatore, SV Seshan, SS Patel… - Modern …, 2020 - nature.com
Abstract SARS-CoV-2, the etiologic agent of COVID-19, is a global pandemic with
substantial mortality dominated by acute respiratory distress syndrome. We systematically …

[HTML][HTML] The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier

TP Buzhdygan, BJ DeOre, A Baldwin-Leclair… - Neurobiology of …, 2020 - Elsevier
As researchers across the globe have focused their attention on understanding SARS-CoV-
2, the picture that is emerging is that of a virus that has serious effects on the vasculature in …

Pathophysiology of SARS-CoV-2: the Mount Sinai COVID-19 autopsy experience

C Bryce, Z Grimes, E Pujadas, S Ahuja, MB Beasley… - Modern …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated clinical
syndrome COVID-19 are causing overwhelming morbidity and mortality around the globe …

Prospects for a safe COVID-19 vaccine

BF Haynes, L Corey, P Fernandes, PB Gilbert… - Science translational …, 2020 - science.org
Rapid development of an efficacious vaccine against the viral pathogen severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), the cause of the coronavirus disease …