[HTML][HTML] Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment
The prevalence of cerebrovascular disease increases with age, placing the elderly at a
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …
Defeating Alzheimer's disease and other dementias: a priority for European science and society
Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …
[HTML][HTML] Atlas of the aging mouse brain reveals white matter as vulnerable foci
Aging is the key risk factor for cognitive decline, yet the molecular changes underlying brain
aging remain poorly understood. Here, we conducted spatiotemporal RNA sequencing of …
aging remain poorly understood. Here, we conducted spatiotemporal RNA sequencing of …
Prevalence of biologically vs clinically defined Alzheimer spectrum entities using the National Institute on Aging–Alzheimer's Association research framework
CR Jack, TM Therneau, SD Weigand, HJ Wiste… - JAMA …, 2019 - jamanetwork.com
Importance A National Institute on Aging–Alzheimer's Association (NIA-AA) workgroup
recently published a research framework in which Alzheimer disease is defined by …
recently published a research framework in which Alzheimer disease is defined by …
Dementia in western Europe: epidemiological evidence and implications for policy making
Dementia is receiving increasing attention from governments and politicians.
Epidemiological research based on western European populations done 20 years ago …
Epidemiological research based on western European populations done 20 years ago …
[HTML][HTML] The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives
Ten years ago we first proposed the Alzheimer's disease (AD) mitochondrial cascade
hypothesis. This hypothesis maintains that gene inheritance defines an individual's baseline …
hypothesis. This hypothesis maintains that gene inheritance defines an individual's baseline …
Depression and risk of developing dementia
AL Byers, K Yaffe - Nature Reviews Neurology, 2011 - nature.com
Depression is highly common throughout the life course and dementia is common in late life.
Depression has been linked with dementia, and growing evidence implies that the timing of …
Depression has been linked with dementia, and growing evidence implies that the timing of …
Optimal preoperative assessment of the geriatric surgical patient: a best practices guideline from the American College of Surgeons National Surgical Quality …
The population of the United States (US) is growing and aging. The US Census Bureau
projects that the number of Americans age 65 years and older will more than double …
projects that the number of Americans age 65 years and older will more than double …
Gender and incidence of dementia in the Framingham Heart Study from mid-adult life
Background Gender-specific risks for dementia and Alzheimer's disease (AD) starting in
midlife remain largely unknown. Methods Prospectively ascertained dementia/AD and cause …
midlife remain largely unknown. Methods Prospectively ascertained dementia/AD and cause …
Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention
C Qiu, M Kivipelto, E Von Strauss - Dialogues in clinical …, 2009 - Taylor & Francis
More than 25 million people in the world today are affected by dementia, most suffering from
Alzheimer's disease. In both developed and developing nations, Alzheimer's disease has …
Alzheimer's disease. In both developed and developing nations, Alzheimer's disease has …