3D cell culture models as recapitulators of the tumor microenvironment for the screening of anti-cancer drugs

MAG Barbosa, CPR Xavier, RF Pereira, V Petrikaitė… - Cancers, 2021 - mdpi.com
Simple Summary Three-dimensional (3D) cell culture models have been proposed as
alternatives for initial drug screening to increase drug development efficiency. In addition to …

Sulfur chemistry in polymer and materials science

H Mutlu, EB Ceper, X Li, J Yang… - Macromolecular …, 2019 - Wiley Online Library
Sulfur and its functional groups are major players in an area of exciting research taking
place in modern polymer and materials science, both in academia and industry. In fact …

Spatiotemporal hydrogel biomaterials for regenerative medicine

TE Brown, KS Anseth - Chemical Society Reviews, 2017 - pubs.rsc.org
Hydrogels mimic many of the physical properties of soft tissue and are widely used
biomaterials for tissue engineering and regenerative medicine. Synthetic hydrogels have …

Achieving controlled biomolecule–biomaterial conjugation

CD Spicer, ET Pashuck, MM Stevens - Chemical reviews, 2018 - ACS Publications
The conjugation of biomolecules can impart materials with the bioactivity necessary to
modulate specific cell behaviors. While the biological roles of particular polypeptide …

Biomaterials and engineered microenvironments to control YAP/TAZ-dependent cell behaviour

G Brusatin, T Panciera, A Gandin, A Citron, S Piccolo - Nature materials, 2018 - nature.com
Mechanical signals are increasingly recognized as overarching regulators of cell behaviour,
controlling stemness, organoid biology, tissue development and regeneration. Moreover …

Colloidal quantum dots: synthesis, composition, structure, and emerging optoelectronic applications

J Zhang, S Zhang, Y Zhang… - Laser & Photonics …, 2023 - Wiley Online Library
In recent decades, quantum dots (QDs) with tunable bandgap, large absorption coefficient,
high quantum yield, multiexciton effect, and easy solution processing have unparalleled …

Hydrogel-mediated sustained systemic delivery of mesenchymal stem cell-derived extracellular vesicles improves hepatic regeneration in chronic liver failure

S Mardpour, MH Ghanian… - … applied materials & …, 2019 - ACS Publications
Extracellular vesicles derived from mesenchymal stem cells (MSC-EVs) have been widely
reported as promising cell-free products that show therapeutic effects of the parental cells …

Thiol–ene click hydrogels for therapeutic delivery

PM Kharkar, MS Rehmann, KM Skeens… - ACS biomaterials …, 2016 - ACS Publications
Hydrogels are of growing interest for the delivery of therapeutics to specific sites in the body.
For use as a delivery vehicle, hydrophilic precursors are usually laden with bioactive …

Degradable hydrogels: Design mechanisms and versatile applications

B Hosseinzadeh, M Ahmadi - Materials Today Sustainability, 2023 - Elsevier
Recent environmental issues raised by the durability of polymers call for designing
degradable products. Hydrogels with widespread applications in superabsorbent and …

Tuning and predicting mesh size and protein release from step growth hydrogels

MS Rehmann, KM Skeens, PM Kharkar… - …, 2017 - ACS Publications
Hydrogel-based depots are of growing interest for release of biopharmaceuticals; however,
a priori selection of hydrogel compositions that will retain proteins of interest and provide …